NF‐κB and HIF crosstalk in immune responses

Hypoxia and inflammation have been associated with a number of pathological conditions, in particular inflammatory diseases. While hypoxia is mainly associated with the activation of hypoxia‐inducible factors (HIFs), inflammation activates the family of transcription factor called nuclear factor‐kap...

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Bibliographic Details
Published in:The FEBS journal 2016-02, Vol.283 (3), p.413-424
Main Authors: D'Ignazio, Laura, Bandarra, Daniel, Rocha, Sonia
Format: Article
Language:English
Subjects:
Animals
B cells
B-Lymphocyte Subsets - immunology
B-Lymphocyte Subsets - metabolism
HIF
Humans
hypoxia
Hypoxia-Inducible Factor 1 - metabolism
IKK
immune response
Immunity - immunology
inflammation
macrophages
Macrophages - immunology
Macrophages - metabolism
neutrophils
Neutrophils - immunology
Neutrophils - metabolism
NF-kappa B - metabolism
NF‐κB
State‐of‐the‐Art Review
State‐of‐the‐Art Reviews
T cells
T-Lymphocyte Subsets - immunology
T-Lymphocyte Subsets - metabolism
T-lymphocytes
transcription factor NF-kappa B
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