Neural correlates of improved executive function following erythropoietin treatment in mood disorders

Cognitive dysfunction in depression and bipolar disorder (BD) is insufficiently targeted by available treatments. Erythropoietin (EPO) increases neuroplasticity and may improve cognition in mood disorders, but the neuronal mechanisms of these effects are unknown. This functional magnetic resonance i...

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Bibliographic Details
Published in:Psychological medicine 2016-06, Vol.46 (8), p.1679-1691
Main Authors: Miskowiak, K. W., Vinberg, M., Glerup, L., Paulson, O. B., Knudsen, G. M., Ehrenreich, H., Harmer, C. J., Kessing, L. V., Siebner, H. R., Macoveanu, J.
Format: Article
Language:English
Subjects:
Adult
Bipolar disorder
Bipolar Disorder - diagnostic imaging
Bipolar Disorder - drug therapy
Bipolar Disorder - physiopathology
Bipolar Disorder - psychology
Blood cells
Blood tests
Brain
Brain - diagnostic imaging
Brain - physiopathology
Brain mapping
Changes
Clinical research
Clinical trials
Cognition
Cognitive ability
Cognitive Dysfunction - diagnostic imaging
Cognitive Dysfunction - drug therapy
Cognitive Dysfunction - physiopathology
Cognitive Dysfunction - psychology
Deactivation
Depression
Depressive Disorder, Major - diagnostic imaging
Depressive Disorder, Major - drug therapy
Depressive Disorder, Major - physiopathology
Depressive Disorder, Major - psychology
Depressive Disorder, Treatment-Resistant - diagnostic imaging
Depressive Disorder, Treatment-Resistant - drug therapy
Depressive Disorder, Treatment-Resistant - physiopathology
Depressive Disorder, Treatment-Resistant - psychology
Disorders
Double-Blind Method
Dysfunction
Emotional disorders
Emotions
Erythrocytes
Erythropoietin
Erythropoietin - therapeutic use
Executive Function
Female
Frontal gyrus
Functional magnetic resonance imaging
Functional Neuroimaging
Functional plasticity
Hippocampal plasticity
Hippocampus
Humans
Magnetic Resonance Imaging
Male
Medical treatment
Memory, Short-Term
Mental depression
Middle Aged
Mood
Neural networks
Neuroimaging
Neuroplasticity
NMR
Nuclear magnetic resonance
Original Articles
Patients
Plasticity
Registration
Remission
Remission (Medicine)
Short term memory
Spatial Memory
Treatment methods
Treatment Outcome
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