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Performance of an active inspired hypoxic guard
Current hypoxic guards systems fail to maintain the inspired O 2 concentration (F I O 2 ) ≥ 21 % across the entire fresh gas flow (FGF) range when a second carrier gas is used (N 2 O or air). We examined the performance of the Maquet O 2 Guard ® , a smart hypoxic guard that increases O 2 delivery if...
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| Published in: | Journal of clinical monitoring and computing 2016-02, Vol.30 (1), p.63-68 |
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| creator | Ghijselings, Idris E. De Cooman, Sofie Carette, Rik Peyton, Philip J. De Wolf, Andre M. Hendrickx, Jan F. A. |
| description | Current hypoxic guards systems fail to maintain the inspired O
2
concentration (F
I
O
2
) ≥ 21 % across the entire fresh gas flow (FGF) range when a second carrier gas is used (N
2
O or air). We examined the performance of the Maquet O
2
Guard
®
, a smart hypoxic guard that increases O
2
delivery if an
inspired
hypoxic mixture is formed. After obtaining IRB approval and informed consent, 12 ASA I-II patients were enrolled. During anesthesia with sevoflurane in O
2
/air, the O
2
Guard
®
was tested by administering O
2
/air at the following
delivered
hypoxic guard limits [expressed as (total FGF in L min
−1
; F
D
O
2
in %)] for 4 min each: [0.3;67], [0.4;50], [0.6;34], [0.8;25], [1.0;21], [1.2;21], [1.5;21], [2;21], [3;21], and [5;21]. The following data were collected: (1) time from F
I
O
2
= 30 to 20 %; (2) time from F
I
O
2
= 20 % to O
2
Guard
®
activation; (3) time from O
2
Guard
®
activation to F
I
O
2
= 25 %; (4) FGF and F
D
O
2
used by the O
2
Guard. If SpO
2
was |
| doi_str_mv | 10.1007/s10877-015-9684-9 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1793241042</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3944285421</sourcerecordid><originalsourceid>FETCH-LOGICAL-c475t-79fbe3e707f532a9bc5cb4d831b82505f080b45706b4bbb2f415347afe3b15d13</originalsourceid><addsrcrecordid>eNqNkMlKBDEQhoMo7g_gRRq8eGmnsnV1jiJuIOhBzyHpTsaW6cVkWpy3N-OMIoLgqQrqq7-oj5AjCmcUACeRQomYA5W5KkqRqw2ySyXynBVUbKael5hTDrhD9mJ8AQBVcrpNdphEiQLkLpk8uOD70JquclnvM9Nlppo3by5rujg0wdXZ82Lo35sqm44m1Adky5tZdIfruk-eri4fL27yu_vr24vzu7wSKOc5Km8ddwjoJWdG2UpWVtTpui2ZBOmhBCskQmGFtZZ5QSUXaLzjlsqa8n1yusodQv86ujjXbRMrN5uZzvVj1BQVZ4KCYP9AC6YKyUSZ0JNf6Es_hi498kkhUqmKRNEVVYU-xuC8HkLTmrDQFPRSvF6J10m8XorXKu0cr5NH27r6e-PLdALYCohp1E1d-HH6z9QPK96LNQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1762771596</pqid></control><display><type>article</type><title>Performance of an active inspired hypoxic guard</title><source>Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List</source><creator>Ghijselings, Idris E. ; De Cooman, Sofie ; Carette, Rik ; Peyton, Philip J. ; De Wolf, Andre M. ; Hendrickx, Jan F. A.</creator><creatorcontrib>Ghijselings, Idris E. ; De Cooman, Sofie ; Carette, Rik ; Peyton, Philip J. ; De Wolf, Andre M. ; Hendrickx, Jan F. A.</creatorcontrib><description>Current hypoxic guards systems fail to maintain the inspired O
2
concentration (F
I
O
2
) ≥ 21 % across the entire fresh gas flow (FGF) range when a second carrier gas is used (N
2
O or air). We examined the performance of the Maquet O
2
Guard
®
, a smart hypoxic guard that increases O
2
delivery if an
inspired
hypoxic mixture is formed. After obtaining IRB approval and informed consent, 12 ASA I-II patients were enrolled. During anesthesia with sevoflurane in O
2
/air, the O
2
Guard
®
was tested by administering O
2
/air at the following
delivered
hypoxic guard limits [expressed as (total FGF in L min
−1
; F
D
O
2
in %)] for 4 min each: [0.3;67], [0.4;50], [0.6;34], [0.8;25], [1.0;21], [1.2;21], [1.5;21], [2;21], [3;21], and [5;21]. The following data were collected: (1) time from F
I
O
2
= 30 to 20 %; (2) time from F
I
O
2
= 20 % to O
2
Guard
®
activation; (3) time from O
2
Guard
®
activation to F
I
O
2
= 25 %; (4) FGF and F
D
O
2
used by the O
2
Guard. If SpO
2
was <90 % for 10 s or longer at any time, the patient was excluded. Three patients were excluded for low SpO
2
. The incidence of F
I
O
2
< 21 % was 100 % within the 1–2 L min
−1
FGF range. The O
2
Guard
®
was activated within 20 s after F
I
O
2
became 20 %, except in one patient where F
I
O
2
oscillated between 20 and 21 %. F
D
O
2
was increased to 60 % and FGF to 1 L min
−1
(the latter only if it was lower than 1 L min
−1
prior to activation of the O
2
Guard). F
I
O
2
increased to 25 % within 55 s after O
2
Guard activation in all patients. The O
2
Guard
®
, an active inspired hypoxic guard, rapidly reverses and limits the duration of inspired hypoxic episodes when the delivered hypoxic guard fails to do so.</description><identifier>ISSN: 1387-1307</identifier><identifier>EISSN: 1573-2614</identifier><identifier>DOI: 10.1007/s10877-015-9684-9</identifier><identifier>PMID: 25757405</identifier><identifier>CODEN: JCMCFG</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Activation ; Adult ; Aged ; Aged, 80 and over ; Anesthesia, Inhalation - instrumentation ; Anesthesia, Inhalation - methods ; Anesthesiology ; Anesthetics, Inhalation - administration & dosage ; Carriers ; Clinical Alarms ; Critical Care Medicine ; Equipment Design ; Equipment Failure Analysis ; Female ; Gas flow ; Guards ; Health Sciences ; Humans ; Hypoxia - prevention & control ; Informed consent ; Intensive ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Monitoring ; Monitoring, Intraoperative - instrumentation ; Monitoring, Intraoperative - methods ; Nitrous Oxide - administration & dosage ; Nitrous Oxide - analysis ; Nitrous oxides ; Original Research ; Oxygen - administration & dosage ; Patients ; Reproducibility of Results ; Sensitivity and Specificity ; Statistics for Life Sciences</subject><ispartof>Journal of clinical monitoring and computing, 2016-02, Vol.30 (1), p.63-68</ispartof><rights>Springer Science+Business Media New York 2015</rights><rights>Springer Science+Business Media Dordrecht 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-79fbe3e707f532a9bc5cb4d831b82505f080b45706b4bbb2f415347afe3b15d13</citedby><cites>FETCH-LOGICAL-c475t-79fbe3e707f532a9bc5cb4d831b82505f080b45706b4bbb2f415347afe3b15d13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25757405$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ghijselings, Idris E.</creatorcontrib><creatorcontrib>De Cooman, Sofie</creatorcontrib><creatorcontrib>Carette, Rik</creatorcontrib><creatorcontrib>Peyton, Philip J.</creatorcontrib><creatorcontrib>De Wolf, Andre M.</creatorcontrib><creatorcontrib>Hendrickx, Jan F. A.</creatorcontrib><title>Performance of an active inspired hypoxic guard</title><title>Journal of clinical monitoring and computing</title><addtitle>J Clin Monit Comput</addtitle><addtitle>J Clin Monit Comput</addtitle><description>Current hypoxic guards systems fail to maintain the inspired O
2
concentration (F
I
O
2
) ≥ 21 % across the entire fresh gas flow (FGF) range when a second carrier gas is used (N
2
O or air). We examined the performance of the Maquet O
2
Guard
®
, a smart hypoxic guard that increases O
2
delivery if an
inspired
hypoxic mixture is formed. After obtaining IRB approval and informed consent, 12 ASA I-II patients were enrolled. During anesthesia with sevoflurane in O
2
/air, the O
2
Guard
®
was tested by administering O
2
/air at the following
delivered
hypoxic guard limits [expressed as (total FGF in L min
−1
; F
D
O
2
in %)] for 4 min each: [0.3;67], [0.4;50], [0.6;34], [0.8;25], [1.0;21], [1.2;21], [1.5;21], [2;21], [3;21], and [5;21]. The following data were collected: (1) time from F
I
O
2
= 30 to 20 %; (2) time from F
I
O
2
= 20 % to O
2
Guard
®
activation; (3) time from O
2
Guard
®
activation to F
I
O
2
= 25 %; (4) FGF and F
D
O
2
used by the O
2
Guard. If SpO
2
was <90 % for 10 s or longer at any time, the patient was excluded. Three patients were excluded for low SpO
2
. The incidence of F
I
O
2
< 21 % was 100 % within the 1–2 L min
−1
FGF range. The O
2
Guard
®
was activated within 20 s after F
I
O
2
became 20 %, except in one patient where F
I
O
2
oscillated between 20 and 21 %. F
D
O
2
was increased to 60 % and FGF to 1 L min
−1
(the latter only if it was lower than 1 L min
−1
prior to activation of the O
2
Guard). F
I
O
2
increased to 25 % within 55 s after O
2
Guard activation in all patients. The O
2
Guard
®
, an active inspired hypoxic guard, rapidly reverses and limits the duration of inspired hypoxic episodes when the delivered hypoxic guard fails to do so.</description><subject>Activation</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anesthesia, Inhalation - instrumentation</subject><subject>Anesthesia, Inhalation - methods</subject><subject>Anesthesiology</subject><subject>Anesthetics, Inhalation - administration & dosage</subject><subject>Carriers</subject><subject>Clinical Alarms</subject><subject>Critical Care Medicine</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Female</subject><subject>Gas flow</subject><subject>Guards</subject><subject>Health Sciences</subject><subject>Humans</subject><subject>Hypoxia - prevention & control</subject><subject>Informed consent</subject><subject>Intensive</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Monitoring</subject><subject>Monitoring, Intraoperative - instrumentation</subject><subject>Monitoring, Intraoperative - methods</subject><subject>Nitrous Oxide - administration & dosage</subject><subject>Nitrous Oxide - analysis</subject><subject>Nitrous oxides</subject><subject>Original Research</subject><subject>Oxygen - administration & dosage</subject><subject>Patients</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Statistics for Life Sciences</subject><issn>1387-1307</issn><issn>1573-2614</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqNkMlKBDEQhoMo7g_gRRq8eGmnsnV1jiJuIOhBzyHpTsaW6cVkWpy3N-OMIoLgqQrqq7-oj5AjCmcUACeRQomYA5W5KkqRqw2ySyXynBVUbKael5hTDrhD9mJ8AQBVcrpNdphEiQLkLpk8uOD70JquclnvM9Nlppo3by5rujg0wdXZ82Lo35sqm44m1Adky5tZdIfruk-eri4fL27yu_vr24vzu7wSKOc5Km8ddwjoJWdG2UpWVtTpui2ZBOmhBCskQmGFtZZ5QSUXaLzjlsqa8n1yusodQv86ujjXbRMrN5uZzvVj1BQVZ4KCYP9AC6YKyUSZ0JNf6Es_hi498kkhUqmKRNEVVYU-xuC8HkLTmrDQFPRSvF6J10m8XorXKu0cr5NH27r6e-PLdALYCohp1E1d-HH6z9QPK96LNQ</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Ghijselings, Idris E.</creator><creator>De Cooman, Sofie</creator><creator>Carette, Rik</creator><creator>Peyton, Philip J.</creator><creator>De Wolf, Andre M.</creator><creator>Hendrickx, Jan F. A.</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7SC</scope><scope>7SP</scope><scope>7U5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>JQ2</scope><scope>K7-</scope><scope>K9.</scope><scope>KB0</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20160201</creationdate><title>Performance of an active inspired hypoxic guard</title><author>Ghijselings, Idris E. ; De Cooman, Sofie ; Carette, Rik ; Peyton, Philip J. ; De Wolf, Andre M. ; Hendrickx, Jan F. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-79fbe3e707f532a9bc5cb4d831b82505f080b45706b4bbb2f415347afe3b15d13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Activation</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anesthesia, Inhalation - instrumentation</topic><topic>Anesthesia, Inhalation - methods</topic><topic>Anesthesiology</topic><topic>Anesthetics, Inhalation - administration & dosage</topic><topic>Carriers</topic><topic>Clinical Alarms</topic><topic>Critical Care Medicine</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Female</topic><topic>Gas flow</topic><topic>Guards</topic><topic>Health Sciences</topic><topic>Humans</topic><topic>Hypoxia - prevention & control</topic><topic>Informed consent</topic><topic>Intensive</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Monitoring</topic><topic>Monitoring, Intraoperative - instrumentation</topic><topic>Monitoring, Intraoperative - methods</topic><topic>Nitrous Oxide - administration & dosage</topic><topic>Nitrous Oxide - analysis</topic><topic>Nitrous oxides</topic><topic>Original Research</topic><topic>Oxygen - administration & dosage</topic><topic>Patients</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Statistics for Life Sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghijselings, Idris E.</creatorcontrib><creatorcontrib>De Cooman, Sofie</creatorcontrib><creatorcontrib>Carette, Rik</creatorcontrib><creatorcontrib>Peyton, Philip J.</creatorcontrib><creatorcontrib>De Wolf, Andre M.</creatorcontrib><creatorcontrib>Hendrickx, Jan F. A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Computer and Information Systems Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Computer Science Collection</collection><collection>Computer Science Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical monitoring and computing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghijselings, Idris E.</au><au>De Cooman, Sofie</au><au>Carette, Rik</au><au>Peyton, Philip J.</au><au>De Wolf, Andre M.</au><au>Hendrickx, Jan F. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Performance of an active inspired hypoxic guard</atitle><jtitle>Journal of clinical monitoring and computing</jtitle><stitle>J Clin Monit Comput</stitle><addtitle>J Clin Monit Comput</addtitle><date>2016-02-01</date><risdate>2016</risdate><volume>30</volume><issue>1</issue><spage>63</spage><epage>68</epage><pages>63-68</pages><issn>1387-1307</issn><eissn>1573-2614</eissn><coden>JCMCFG</coden><abstract>Current hypoxic guards systems fail to maintain the inspired O
2
concentration (F
I
O
2
) ≥ 21 % across the entire fresh gas flow (FGF) range when a second carrier gas is used (N
2
O or air). We examined the performance of the Maquet O
2
Guard
®
, a smart hypoxic guard that increases O
2
delivery if an
inspired
hypoxic mixture is formed. After obtaining IRB approval and informed consent, 12 ASA I-II patients were enrolled. During anesthesia with sevoflurane in O
2
/air, the O
2
Guard
®
was tested by administering O
2
/air at the following
delivered
hypoxic guard limits [expressed as (total FGF in L min
−1
; F
D
O
2
in %)] for 4 min each: [0.3;67], [0.4;50], [0.6;34], [0.8;25], [1.0;21], [1.2;21], [1.5;21], [2;21], [3;21], and [5;21]. The following data were collected: (1) time from F
I
O
2
= 30 to 20 %; (2) time from F
I
O
2
= 20 % to O
2
Guard
®
activation; (3) time from O
2
Guard
®
activation to F
I
O
2
= 25 %; (4) FGF and F
D
O
2
used by the O
2
Guard. If SpO
2
was <90 % for 10 s or longer at any time, the patient was excluded. Three patients were excluded for low SpO
2
. The incidence of F
I
O
2
< 21 % was 100 % within the 1–2 L min
−1
FGF range. The O
2
Guard
®
was activated within 20 s after F
I
O
2
became 20 %, except in one patient where F
I
O
2
oscillated between 20 and 21 %. F
D
O
2
was increased to 60 % and FGF to 1 L min
−1
(the latter only if it was lower than 1 L min
−1
prior to activation of the O
2
Guard). F
I
O
2
increased to 25 % within 55 s after O
2
Guard activation in all patients. The O
2
Guard
®
, an active inspired hypoxic guard, rapidly reverses and limits the duration of inspired hypoxic episodes when the delivered hypoxic guard fails to do so.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>25757405</pmid><doi>10.1007/s10877-015-9684-9</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1387-1307 |
| ispartof | Journal of clinical monitoring and computing, 2016-02, Vol.30 (1), p.63-68 |
| issn | 1387-1307 1573-2614 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1793241042 |
| source | Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List |
| subjects | Activation Adult Aged Aged, 80 and over Anesthesia, Inhalation - instrumentation Anesthesia, Inhalation - methods Anesthesiology Anesthetics, Inhalation - administration & dosage Carriers Clinical Alarms Critical Care Medicine Equipment Design Equipment Failure Analysis Female Gas flow Guards Health Sciences Humans Hypoxia - prevention & control Informed consent Intensive Male Medicine Medicine & Public Health Middle Aged Monitoring Monitoring, Intraoperative - instrumentation Monitoring, Intraoperative - methods Nitrous Oxide - administration & dosage Nitrous Oxide - analysis Nitrous oxides Original Research Oxygen - administration & dosage Patients Reproducibility of Results Sensitivity and Specificity Statistics for Life Sciences |
| title | Performance of an active inspired hypoxic guard |
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