Decrease of delta oscillatory responses is associated with increased age in healthy elderly

The purpose of this study was to investigate changes in delta event-related oscillations (EROs) in younger and older healthy elderly subjects. We hypothesized that delta EROs were affected by age-related changes, which could be reflected in a visual oddball paradigm. The study included two groups of...

Full description

Saved in:
Bibliographic Details
Published in:International journal of psychophysiology 2016-05, Vol.103, p.103-109
Main Authors: Emek-Savaş, Derya Durusu, Güntekin, Bahar, Yener, Görsev G., Başar, Erol
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aged, 80 and over
Aging
Aging - physiology
Biological Clocks - physiology
Brain - physiology
Delta
Delta Rhythm - physiology
Electroencephalography
Event-related oscillations
Female
Healthy elderly
Humans
Male
Middle Aged
P300
Photic Stimulation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The purpose of this study was to investigate changes in delta event-related oscillations (EROs) in younger and older healthy elderly subjects. We hypothesized that delta EROs were affected by age-related changes, which could be reflected in a visual oddball paradigm. The study included two groups of subjects, 17 younger healthy elderly (mean age: 63.1±2.8years) and 17 gender- and education-matched older healthy elderly (mean age: 79.6±5.2years), who performed a visual oddball paradigm. EEG was recorded from F3, Fz, F4, C3, Cz, C4, P3, Pz, P4, O1, Oz and O2 locations. Peak-to-peak amplitudes of delta (0.5–3Hz) target ERO responses during the post-stimulus 0–800ms time window were measured. Repeated measures of ANOVA was used to analyze four locations (frontal, central, parietal, occipital), at three sagittal (left, midline, right) sites. Independent t-tests were applied for post-hoc analyses. The older healthy elderly group had 16–25% lower values for the maximum peak-to-peak amplitudes of delta ERO compared with the younger healthy elderly group over frontal (p
ISSN:0167-8760
1872-7697
DOI:10.1016/j.ijpsycho.2015.02.006