The evidence for low-dose CT screening of lung cancer

Abstract Lung cancer remains the leading cause of cancer-related death in the United States. An effective screening tool for early lung cancer detection has long been sought. Early chest radiograph and low-dose computed tomography (LDCT) screening trials were promising and demonstrated increased can...

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Bibliographic Details
Published in:Clinical imaging 2016-03, Vol.40 (2), p.288-295
Main Authors: Ruchalski, Kathleen, Gutierrez, Antonio, Genshaft, Scott, Abtin, Fereidoun, Suh, Robert
Format: Article
Language:English
Subjects:
Cancer
Cancer therapies
Cellular biology
Computation
Early Detection of Cancer - methods
Humans
Imaging
Lung cancer
Lung cancer screening
Lung Neoplasms - diagnostic imaging
Lung-RADS
Lungs
Medical imaging
Medical screening
Morality
Mortality
Nelson
NLST
Ostomy
Patients
Radiation Dosage
Radiographs
Radiography
Radiology
Screening
Smoking
Studies
Thoracic surgery
Tomography
Tomography, X-Ray Computed - methods
Tumors
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Summary:Abstract Lung cancer remains the leading cause of cancer-related death in the United States. An effective screening tool for early lung cancer detection has long been sought. Early chest radiograph and low-dose computed tomography (LDCT) screening trials were promising and demonstrated increased cancer detection. However, these studies were not able to improve lung cancer mortality. The National Lung Screening Trial resulted in decreased lung cancer mortality with LDCT screening in a high-risk population. Similar trials are currently underway in Europe. With LDCT now being widely implemented, it is paramount for radiologists to understand the evidence for lung cancer screening.
ISSN:0899-7071
1873-4499
DOI:10.1016/j.clinimag.2015.07.001