Intrauterine versus extrauterine influences on adult disease risk: epidemiological aspects and sociocultural issues

In this context, the paper by Corsi et al 1 prompts one to reflect on some important epidemiological as well as social issues that relate to the intergenerational transmission of disease risk in the global perspective. Since the inception of the developmental origins hypothesis as one of the explana...

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Bibliographic Details
Published in:Archives of disease in childhood 2015-10, Vol.100 (10), p.905-906
Main Authors: Krishnaveni, Ghattu V, Kumaran, Kalyanaraman
Format: Article
Language:English
Subjects:
Adiposity
Analysis
Body Composition
Body Mass Index
Body Weight
Communicable Diseases
Diabetes
Disease transmission
Environmental factors
Environmental Influences
Epidemiology
Female
Females
Health risk assessment
Health risks
Humans
Male
Mother and child
Mother-child relations
Mothers
Nutrition
Obesity
Offspring
Parent Role
Pediatric Obesity - etiology
Physical Environment
Pregnancy
Risk factors
Scientific Concepts
Studies
Type 2 diabetes
Womens health
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Summary:In this context, the paper by Corsi et al 1 prompts one to reflect on some important epidemiological as well as social issues that relate to the intergenerational transmission of disease risk in the global perspective. Since the inception of the developmental origins hypothesis as one of the explanations for the sudden rise in the prevalence of type 2 diabetes and other NCDs, especially in low-income and middle-income countries such as India, 2 the number of studies exploring the role of maternal intrauterine environment on offspring NCD risk has increased greatly. [...]the overall social implications of attributing offspring disease outcomes to either intrauterine or extrauterine environmental factors should be considered.
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2015-308942