Association of FTO and IRX3 genetic variants to obesity risk in north India

Background: Obesity is an increasingly important health problem worldwide as well as in developing countries like India. Recent genetic studies suggest that obesity associated FTO and IRX3 are functionally linked and many effects due to genetic variants in FTO gene act through IRX3. Aim: To evaluate...

Full description

Saved in:
Bibliographic Details
Published in:Annals of human biology 2016-09, Vol.43 (5), p.451-456
Main Authors: Srivastava, Apurva, Mittal, Balraj, Prakash, Jai, Srivastava, Pranjal, Srivastava, Nimisha, Srivastava, Neena
Format: Article
Language:English
Subjects:
Adult
Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics
Female
generalised multifactor dimensionality reduction
Genetic Association Studies
Genetic Loci
Genetic Predisposition to Disease
haplotypes
Haplotypes - genetics
Homeodomain Proteins - genetics
Humans
India
Linkage disequilibrium
Linkage Disequilibrium - genetics
Logistic Models
Male
Multifactor Dimensionality Reduction
Obesity - genetics
Polymorphism, Single Nucleotide - genetics
Risk Factors
Transcription Factors - genetics
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: Obesity is an increasingly important health problem worldwide as well as in developing countries like India. Recent genetic studies suggest that obesity associated FTO and IRX3 are functionally linked and many effects due to genetic variants in FTO gene act through IRX3. Aim: To evaluate the association of FTO and IRX3 genetic variants towards obesity risk. Subjects and methods: North Indian individuals categorised as non-obese (BMI 
ISSN:0301-4460
1464-5033
DOI:10.3109/03014460.2015.1103902