Perioperative and oncologic outcomes of minimally invasive liver resection for colorectal metastases: A case–control study of 130 patients

• Published in: Surgery 2016-10, Vol.160 (4), p.1097-1103
• Main Authors: Karagkounis, Georgios, MD, Akyuz, Muhammet, MD, Guerron, Alfredo Daniel, MD, Yazici, Pinar, MD, Aucejo, Federico N., MD, Quintini, Cristiano, MD, Miller, Charles M., MD, Vogt, David P., MD, Fung, John J., MD, PhD, Berber, Eren, MD
• Format: Article
• Language: English
• Subjects: Adult; Aged; Case-Control Studies; Colorectal Neoplasms - mortality; Colorectal Neoplasms - pathology; Colorectal Neoplasms - surgery; Disease-Free Survival; Female; Follow-Up Studies; Hepatectomy - methods; Hepatectomy - mortality; Humans; Laparoscopy - methods; Laparoscopy - mortality; Laparotomy - methods; Laparotomy - mortality; Length of Stay; Liver Neoplasms - mortality; Liver Neoplasms - secondary; Liver Neoplasms - surgery; Male; Middle Aged; Minimally Invasive Surgical Procedures - methods; Minimally Invasive Surgical Procedures - mortality; Neoplasm Recurrence, Local - mortality; Neoplasm Recurrence, Local - pathology; Neoplasm Recurrence, Local - surgery; Neoplasm Staging; Patient Selection; Risk Assessment; Surgery; Survival Analysis; Treatment Outcome
• ISSN: 0039-6060; 1532-7361
• DOI: 10.1016/j.surg.2016.04.043

Background Our aim was to compare the perioperative and oncologic outcomes of open liver resection and minimally invasive liver resection in the management of colorectal liver metastases. Methods Patients who underwent minimally invasive liver resection for colorectal liver metastases between January 2006 and June 2015 at a single center were identified and matched by extent of resection to consecutive open liver resection patients from the same period. Clinicopathologic characteristics, perioperative data, recurrence, and survival outcomes were collected and analyzed based on intention-to-treat. Results Sixty-five patients underwent minimally invasive liver resection during this period and were matched to 65 consecutive open liver resection patients, with similar baseline demographic, tumor, and chemotherapy parameters. Conversion to open occurred in 5 (7.7%) minimally invasive liver resection patients. R0 resection rates and operative times were comparable, but the estimated blood loss was less in the minimally invasive liver resection group (median 200 mL vs 400 mL, P