Do systemic antibiotics prevent dry socket and infection after third molar extraction? A systematic review and meta-analysis

The use of antibiotics to prevent dry socket and infection is a controversial but widespread practice. The aim of the study is to assess the efficacy of systemic antibiotics in reducing the frequencies of these complications after extraction. A systematic review and meta-analysis, according to the P...

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Bibliographic Details
Published in:Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2016-10, Vol.122 (4), p.403-425
Main Authors: Ramos, Eva, Santamaría, Joseba, Santamaría, Gorka, Barbier, Luis, Arteagoitia, Icíar
Format: Article
Language:English
Subjects:
Antibiotic Prophylaxis
Dentistry
Dry Socket - prevention & control
Humans
Molar, Third - surgery
Postoperative Complications - prevention & control
Tooth Extraction
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Summary:The use of antibiotics to prevent dry socket and infection is a controversial but widespread practice. The aim of the study is to assess the efficacy of systemic antibiotics in reducing the frequencies of these complications after extraction. A systematic review and meta-analysis, according to the PRISMA statement, based on randomized double-blind placebo-controlled trials evaluating systemic antibiotics to prevent dry socket and infection after third molar surgery. Databases were searched up to June 2015. Relative risks (RRs) were calculated with inverse variance-weighted, fixed-effect, or random-effect models. We included 22 papers in the qualitative and 21 in the quantitative review (3304 extractions). Overall-RR was 0.43 (95% confidence interval [CI] 0.33-0.56; P 
ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2016.04.016