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Influence of remote monitoring on long-term cardiovascular outcomes after cardioverter-defibrillator implantation

Abstract Aims Device-based remote monitoring (RM) has been linked to improved clinical outcomes at short to medium-term follow-up. Whether this benefit extends to long-term follow-up is unknown. We sought to assess the effect of device-based RM on long-term clinical outcomes in recipients of implant...

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Bibliographic Details
Published in:International journal of cardiology 2016-11, Vol.222, p.764-768
Main Authors: Portugal, Guilherme, Cunha, Pedro, Valente, Bruno, Feliciano, Joana, Lousinha, Ana, Alves, Sandra, Braz, Manuel, Pimenta, Ricardo, Delgado, Ana Sofia, Oliveira, Mário, Ferreira, Rui C
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Language:English
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Summary:Abstract Aims Device-based remote monitoring (RM) has been linked to improved clinical outcomes at short to medium-term follow-up. Whether this benefit extends to long-term follow-up is unknown. We sought to assess the effect of device-based RM on long-term clinical outcomes in recipients of implantable cardioverter-defibrillators(ICD). Methods Retrospective cohort study of consecutive patients who underwent ICD implantation for primary prevention. RM was initiated with patient consent according to availability of RM hardware at implantation. Patients with concomitant cardiac resynchronization therapy were excluded. Data on hospitalizations, mortality and cause of death were systematically assessed using a nationwide healthcare platform. A Cox proportional hazards model was employed to estimate the effect of RM on mortality and a composite endpoint of cardiovascular mortality and hospital admission due to heart failure (HF). Results 312 patients were included with a median follow-up of 37.7 months (range 1 to 146). 121 patients (38.2%) were under RM since the first outpatient visit post-ICD and 191 were in conventional follow-up. No differences were found regarding age, left ventricular ejection fraction, heart failure etiology or NYHA class at implantation. Patients under RM had higher long-term survival (hazard ratio[HR] 0.50, CI 0.27–0.93, p = 0.029) and lower incidence of the composite outcome (HR 0.47, CI 0.27–0.82, p = 0.008). After multivariate survival analysis, overall survival was independently associated with younger age, higher LVEF, NYHA class lower than 3 and RM. Conclusion RM was independently associated with increased long-term survival and a lower incidence of a composite endpoint of hospitalization for HF or cardiovascular mortality.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2016.07.157