The effect of dietary intake of sesame (Sesamumindicum L.) derivatives related to the lipid profile and blood pressure: A systematic review

In this systematic review, we discuss the scientific evidence about the effect of dietary intake of seeds and sesame derivatives on lipid profile and blood pressure (BP) of hypertensive and dyslipidemic individuals. Clinical trials published in English, Portuguese or Spanish were searched on the fol...

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Bibliographic Details
Published in:Critical reviews in food science and nutrition 2018-01, Vol.58 (1), p.116-125
Main Authors: Cardoso, Carolina Alves, Oliveira, Gláucia Maria Moraes de, Gouveia, Luciana de Almeida Vittori, Moreira, Annie Seixas Bello, Rosa, Glorimar
Format: Article
Language:English
Subjects:
Bias
Blood Pressure
cardiovascular disease
Clinical trials
Clinical Trials as Topic
Derivatives
Design standards
Diet
Dietary intake
Dyslipidemia
Dyslipidemias - drug therapy
Humans
Hypertension
Hypertension - drug therapy
Ingestion
Lipids
Lipids - blood
Literature reviews
Medical research
Metabolic disorders
Plant Extracts - therapeutic use
Risk analysis
risk factors
Seeds
Selection Bias
sesame oil
Sesame Oil - therapeutic use
Sesamum
Sesamum - chemistry
Sesamum indicum
Systematic review
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Summary:In this systematic review, we discuss the scientific evidence about the effect of dietary intake of seeds and sesame derivatives on lipid profile and blood pressure (BP) of hypertensive and dyslipidemic individuals. Clinical trials published in English, Portuguese or Spanish were searched on the following databases: Lilacs, PubMed, Isi Web of Knowledge, Cochrane Library, Scopus, Trip Data Base and Scielo. The bibliographic search period was started in September 2013 and ended in January 2014. The biases of risk analysis were carried out considering 6 of the 8 criteria of the Cochrane Handbook for Systematic Reviews of Interventions Version 5.1. Of the 7 clinical trials included, five evaluating individuals with hypertension observed a significant reduction in systolic and/or diastolic blood pressure. The two articles that evaluated individuals with dyslipidemia showed improvement in lipid profile. The mechanisms of action are still being studied. Regarding the bias risk analysis, clinical trials included showed few descriptions of the methods applied. There are few studies about sesame ingestion, and it was observed high risk for bias in the selected studies. More standardized methods with attention to the design of studies are needed to improve the level of the evidence.
ISSN:1040-8398
1549-7852
DOI:10.1080/10408398.2015.1137858