Evaluation of choroidal thickness in psoriasis using optical coherence tomography

• Published in: International ophthalmology 2016-12, Vol.36 (6), p.851-854
• Main Authors: Türkcü, Fatih Mehmet, Şahin, Alparslan, Yüksel, Harun, Akkurt, Meltem, Uçmak, Derya, Çınar, Yasin, Yıldırım, Adnan, Çaça, İhsan
• Format: Article
• Language: English
• Subjects: Adult; Aged; Case-Control Studies; Choroid - diagnostic imaging; Choroid - pathology; Female; Fluorescein Angiography; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Ophthalmology; Original Paper; Prospective Studies; Psoriasis - pathology; Severity of Illness Index; Tomography, Optical Coherence - methods; Uveitis - pathology; Visual Acuity; Young Adult
• ISSN: 0165-5701; 1573-2630
• DOI: 10.1007/s10792-016-0212-9

The purpose of this study was to evaluate choroidal thickness (CT) in patients with psoriasis using enhanced depth imaging optical coherence tomography (EDI-OCT) and to determine its relationship with psoriasis activity indices. In this prospective study, EDI-OCT images were obtained in consecutive patients with psoriasis and in age–gender-matched healthy individuals. Comprehensive ophthalmic examination and EDI-OCT evaluation were performed. CT was measured in the subfoveal area. Correlation analyses were performed to identify the relationship of the CT with disease duration and clinical disease activity score. In total, 65 individuals were evaluated in this study, 35 with psoriasis and 30 controls. The mean disease duration of the patients with psoriasis was 15.7 ± 8.8 years (0.3–34 years). There was no difference between groups with respect to age and gender ( p  = 0.695 and p  = 0.628, respectively). Five of the 35 patients with psoriasis had anterior uveitis. None of the patients with psoriasis had signs of posterior uveitis. CT was significantly higher in the psoriasis group than that of control subjects ( p