Comparison of Recent Trends in Patients With and Without Major Depression and Acute ST-Elevation Myocardial Infarction

Abstract Depression has been associated with adverse outcomes after acute coronary syndrome (ACS), including ST-elevation myocardial infarction (STEMI). However, trends over time in the incidence and in-hospital treatment of STEMI for patients with comorbid depression in the current era are unknown....

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Bibliographic Details
Published in:The American journal of cardiology 2016-09, Vol.118 (6), p.779-784
Main Authors: Schulman-Marcus, Joshua, MD, Shah, Tara, MD, Swaminathan, Rajesh V., MD, Feldman, Dmitriy N., MD, Wong, Shing-Chiu, MD, Singh, Harsimran S., MD, Minutello, Robert M., MD, Bergman, Geoffrey, MD, Kim, Luke K., MD
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Age
Aged
Aged, 80 and over
Cardiovascular
Codes
Comorbidity
Confidence intervals
Coronary vessels
Cross-Sectional Studies
Depressive Disorder, Major - epidemiology
European Continental Ancestry Group - statistics & numerical data
Female
Heart attacks
Hemodialysis
Hospital Mortality - trends
Hospitals
Humans
Incidence
Logistic Models
Male
Mens health
Mental depression
Middle Aged
Morbidity
Mortality
Multivariate Analysis
Odds Ratio
Patients
Percutaneous Coronary Intervention - utilization
Sex Factors
ST Elevation Myocardial Infarction - epidemiology
ST Elevation Myocardial Infarction - surgery
Trends
Variables
Womens health
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Summary:Abstract Depression has been associated with adverse outcomes after acute coronary syndrome (ACS), including ST-elevation myocardial infarction (STEMI). However, trends over time in the incidence and in-hospital treatment of STEMI for patients with comorbid depression in the current era are unknown. We conducted a serial, cross-sectional analysis of STEMI patients (weighted n=3,057,998) in the National Inpatient Sample from 2003-2012. We examined trends in STEMI incidence and percutaneous coronary intervention (PCI) for patients with and without depression. We used multivariate logistic regression to assess observed differences as well as to explore trends in in-hospital mortality. Depression was present in 153,180 (5%) of the sample. Patients with depression were more likely to be female (55% vs 37%), of white race (86% vs 78%), and had lower crude mortality (12.0% vs 14.2%; p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2016.06.051