Potential DNA binding and nuclease functions of ComEC domains characterized in silico

Bacterial competence, which can be natural or induced, allows the uptake of exogenous double stranded DNA (dsDNA) into a competent bacterium. This process is known as transformation. A multiprotein assembly binds and processes the dsDNA to import one strand and degrade another yet the underlying mol...

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Bibliographic Details
Published in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 2016-10, Vol.84 (10), p.1431-1442
Main Authors:	Baker, James A., Simkovic, Felix, Taylor, Helen M.C., Rigden, Daniel J.
Format:	Article
Language:	English
Subjects:	Amino Acid Sequence Bacillus subtilis Bacillus subtilis - genetics Bacillus subtilis - metabolism bacterial competence Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism beta-Lactamases - chemistry beta-Lactamases - genetics beta-Lactamases - metabolism Binding Sites Bioinformatics ComEC Conserved Sequence Deoxyribonucleases - chemistry Deoxyribonucleases - genetics Deoxyribonucleases - metabolism Deoxyribonucleic acid DNA DNA - chemistry DNA - metabolism DNA-Binding Proteins - chemistry DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism domain structure evolutionary covariance Gene Expression Molecular Docking Simulation Protein Binding Protein Domains protein modeling Protein Structure, Secondary Sequence Alignment Static Electricity Structural Homology, Protein Structure-Activity Relationship Transformation, Bacterial
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