Loading…
Detection of genes with deleterious alleles in an inbred line of tilapia ( Oreochromis aureus)
An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny...
Saved in:
| Published in: | Aquaculture 2002-04, Vol.206 (3), p.151-164 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c395t-96782487bcd04459089e4fd659f6fe5b1314d004d7e658e84e3b500aed6d50e93 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c395t-96782487bcd04459089e4fd659f6fe5b1314d004d7e658e84e3b500aed6d50e93 |
| container_end_page | 164 |
| container_issue | 3 |
| container_start_page | 151 |
| container_title | Aquaculture |
| container_volume | 206 |
| creator | Palti, Y Shirak, A Cnaani, A Hulata, G Avtalion, R.R Ron, M |
| description | An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic
Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny of the fourth successive generation of meiogynogenetic
O. aureus was screened with 76 microsatellite DNA markers to identify polymorphic loci. Twenty polymorphic markers were tested for segregation distortion in four crosses of informative progeny to identify linkage to genes with recessive deleterious alleles. Significant distortion (
P |
| doi_str_mv | 10.1016/S0044-8486(01)00727-X |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_18307931</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S004484860100727X</els_id><sourcerecordid>18307931</sourcerecordid><originalsourceid>FETCH-LOGICAL-c395t-96782487bcd04459089e4fd659f6fe5b1314d004d7e658e84e3b500aed6d50e93</originalsourceid><addsrcrecordid>eNqFkV1rFTEQhkNR8Fj9CUIoVNqL1cnmY7NXUlq_oNALFXplyElm25Q0OU12lf57c3pKBW-8yRDyvJN33iHkDYN3DJh6_w1AiE4LrY6AHQMM_dBd7pEV0wPvpOr7Z2T1hLwgL2u9AQClJFuRn2c4o5tDTjRP9AoTVvo7zNfUY2wvJeSlUhtju1UaErWpneuCnsaQcKuZQ7SbYOkRvSiY3XXJt6FJloJLPX5Fnk82Vnz9WPfJj08fv59-6c4vPn89PTnvHB_l3I1q0L3Qw9r55lOOoEcUk1dynNSEcs04E76N4AdUUqMWyNcSwKJXXgKOfJ-83fXdlHy3YJ1NM-EwRpuwTWCY5jCMnDXw4B_wJi8lNW-mB6H0qLVukNxBruRaC05mU8KtLfeGgdlGbh4iN9s8DTDzELm5bLrDx-a2OhunYpML9a-YK9YzLhr3Ycdhi-RXwGKqC5gc-lDaMozP4T8__QHdtZSR</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>204689888</pqid></control><display><type>article</type><title>Detection of genes with deleterious alleles in an inbred line of tilapia ( Oreochromis aureus)</title><source>ScienceDirect Freedom Collection</source><creator>Palti, Y ; Shirak, A ; Cnaani, A ; Hulata, G ; Avtalion, R.R ; Ron, M</creator><creatorcontrib>Palti, Y ; Shirak, A ; Cnaani, A ; Hulata, G ; Avtalion, R.R ; Ron, M</creatorcontrib><description>An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic
Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny of the fourth successive generation of meiogynogenetic
O. aureus was screened with 76 microsatellite DNA markers to identify polymorphic loci. Twenty polymorphic markers were tested for segregation distortion in four crosses of informative progeny to identify linkage to genes with recessive deleterious alleles. Significant distortion (
P<0.0001) from the expected Mendelian segregation was identified for three unlinked markers:
UNH159,
UNH216 and
UNH231. A significant deleterious effect (
P<0.05) was detected in at least two crosses for each of the three markers. The onset of the deleterious process occurred between days 4 and 8 after fertilization in family 2 for
UNH159 and
UNH216 with significant epistatic interaction (
P≤0.0001) between the two loci. In family 4, the onset was shown to occur by day 4 in early spawns and at a much later developmental stage in late spawns. The differences detected in marker effect among crosses and between spawns of the same cross indicate that complex mechanisms are involved. DNA markers linked to genes with deleterious alleles can aid in identification and elimination of those alleles from inbred lines of
O. aureus.</description><identifier>ISSN: 0044-8486</identifier><identifier>EISSN: 1873-5622</identifier><identifier>DOI: 10.1016/S0044-8486(01)00727-X</identifier><identifier>CODEN: AQCLAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Animal aquaculture ; Animal productions ; Animals ; Aquaculture ; Biological and medical sciences ; Classical genetics, quantitative genetics, hybrids ; Deleterious genes ; DNA markers ; fish culture ; Freshwater ; Fundamental and applied biological sciences. Psychology ; Genes ; Genetics of eukaryotes. Biological and molecular evolution ; Genomics ; Gynogenesis ; Oreochromis aureus ; Pisciculture ; Tilapia ; Vertebrata ; Vertebrate aquaculture</subject><ispartof>Aquaculture, 2002-04, Vol.206 (3), p.151-164</ispartof><rights>2002 Elsevier Science B.V.</rights><rights>2002 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. Apr 22, 2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c395t-96782487bcd04459089e4fd659f6fe5b1314d004d7e658e84e3b500aed6d50e93</citedby><cites>FETCH-LOGICAL-c395t-96782487bcd04459089e4fd659f6fe5b1314d004d7e658e84e3b500aed6d50e93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13612134$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Palti, Y</creatorcontrib><creatorcontrib>Shirak, A</creatorcontrib><creatorcontrib>Cnaani, A</creatorcontrib><creatorcontrib>Hulata, G</creatorcontrib><creatorcontrib>Avtalion, R.R</creatorcontrib><creatorcontrib>Ron, M</creatorcontrib><title>Detection of genes with deleterious alleles in an inbred line of tilapia ( Oreochromis aureus)</title><title>Aquaculture</title><description>An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic
Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny of the fourth successive generation of meiogynogenetic
O. aureus was screened with 76 microsatellite DNA markers to identify polymorphic loci. Twenty polymorphic markers were tested for segregation distortion in four crosses of informative progeny to identify linkage to genes with recessive deleterious alleles. Significant distortion (
P<0.0001) from the expected Mendelian segregation was identified for three unlinked markers:
UNH159,
UNH216 and
UNH231. A significant deleterious effect (
P<0.05) was detected in at least two crosses for each of the three markers. The onset of the deleterious process occurred between days 4 and 8 after fertilization in family 2 for
UNH159 and
UNH216 with significant epistatic interaction (
P≤0.0001) between the two loci. In family 4, the onset was shown to occur by day 4 in early spawns and at a much later developmental stage in late spawns. The differences detected in marker effect among crosses and between spawns of the same cross indicate that complex mechanisms are involved. DNA markers linked to genes with deleterious alleles can aid in identification and elimination of those alleles from inbred lines of
O. aureus.</description><subject>Animal aquaculture</subject><subject>Animal productions</subject><subject>Animals</subject><subject>Aquaculture</subject><subject>Biological and medical sciences</subject><subject>Classical genetics, quantitative genetics, hybrids</subject><subject>Deleterious genes</subject><subject>DNA markers</subject><subject>fish culture</subject><subject>Freshwater</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genes</subject><subject>Genetics of eukaryotes. Biological and molecular evolution</subject><subject>Genomics</subject><subject>Gynogenesis</subject><subject>Oreochromis aureus</subject><subject>Pisciculture</subject><subject>Tilapia</subject><subject>Vertebrata</subject><subject>Vertebrate aquaculture</subject><issn>0044-8486</issn><issn>1873-5622</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNqFkV1rFTEQhkNR8Fj9CUIoVNqL1cnmY7NXUlq_oNALFXplyElm25Q0OU12lf57c3pKBW-8yRDyvJN33iHkDYN3DJh6_w1AiE4LrY6AHQMM_dBd7pEV0wPvpOr7Z2T1hLwgL2u9AQClJFuRn2c4o5tDTjRP9AoTVvo7zNfUY2wvJeSlUhtju1UaErWpneuCnsaQcKuZQ7SbYOkRvSiY3XXJt6FJloJLPX5Fnk82Vnz9WPfJj08fv59-6c4vPn89PTnvHB_l3I1q0L3Qw9r55lOOoEcUk1dynNSEcs04E76N4AdUUqMWyNcSwKJXXgKOfJ-83fXdlHy3YJ1NM-EwRpuwTWCY5jCMnDXw4B_wJi8lNW-mB6H0qLVukNxBruRaC05mU8KtLfeGgdlGbh4iN9s8DTDzELm5bLrDx-a2OhunYpML9a-YK9YzLhr3Ycdhi-RXwGKqC5gc-lDaMozP4T8__QHdtZSR</recordid><startdate>20020422</startdate><enddate>20020422</enddate><creator>Palti, Y</creator><creator>Shirak, A</creator><creator>Cnaani, A</creator><creator>Hulata, G</creator><creator>Avtalion, R.R</creator><creator>Ron, M</creator><general>Elsevier B.V</general><general>Elsevier Science</general><general>Elsevier Sequoia S.A</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QR</scope><scope>7ST</scope><scope>7TN</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>F1W</scope><scope>FR3</scope><scope>H94</scope><scope>H95</scope><scope>H98</scope><scope>H99</scope><scope>L.F</scope><scope>L.G</scope><scope>M7N</scope><scope>P64</scope><scope>SOI</scope></search><sort><creationdate>20020422</creationdate><title>Detection of genes with deleterious alleles in an inbred line of tilapia ( Oreochromis aureus)</title><author>Palti, Y ; Shirak, A ; Cnaani, A ; Hulata, G ; Avtalion, R.R ; Ron, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-96782487bcd04459089e4fd659f6fe5b1314d004d7e658e84e3b500aed6d50e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Animal aquaculture</topic><topic>Animal productions</topic><topic>Animals</topic><topic>Aquaculture</topic><topic>Biological and medical sciences</topic><topic>Classical genetics, quantitative genetics, hybrids</topic><topic>Deleterious genes</topic><topic>DNA markers</topic><topic>fish culture</topic><topic>Freshwater</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genes</topic><topic>Genetics of eukaryotes. Biological and molecular evolution</topic><topic>Genomics</topic><topic>Gynogenesis</topic><topic>Oreochromis aureus</topic><topic>Pisciculture</topic><topic>Tilapia</topic><topic>Vertebrata</topic><topic>Vertebrate aquaculture</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Palti, Y</creatorcontrib><creatorcontrib>Shirak, A</creatorcontrib><creatorcontrib>Cnaani, A</creatorcontrib><creatorcontrib>Hulata, G</creatorcontrib><creatorcontrib>Avtalion, R.R</creatorcontrib><creatorcontrib>Ron, M</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Chemoreception Abstracts</collection><collection>Environment Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Aquaculture Abstracts</collection><collection>ASFA: Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Aquaculture</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Palti, Y</au><au>Shirak, A</au><au>Cnaani, A</au><au>Hulata, G</au><au>Avtalion, R.R</au><au>Ron, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection of genes with deleterious alleles in an inbred line of tilapia ( Oreochromis aureus)</atitle><jtitle>Aquaculture</jtitle><date>2002-04-22</date><risdate>2002</risdate><volume>206</volume><issue>3</issue><spage>151</spage><epage>164</epage><pages>151-164</pages><issn>0044-8486</issn><eissn>1873-5622</eissn><coden>AQCLAL</coden><abstract>An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic
Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny of the fourth successive generation of meiogynogenetic
O. aureus was screened with 76 microsatellite DNA markers to identify polymorphic loci. Twenty polymorphic markers were tested for segregation distortion in four crosses of informative progeny to identify linkage to genes with recessive deleterious alleles. Significant distortion (
P<0.0001) from the expected Mendelian segregation was identified for three unlinked markers:
UNH159,
UNH216 and
UNH231. A significant deleterious effect (
P<0.05) was detected in at least two crosses for each of the three markers. The onset of the deleterious process occurred between days 4 and 8 after fertilization in family 2 for
UNH159 and
UNH216 with significant epistatic interaction (
P≤0.0001) between the two loci. In family 4, the onset was shown to occur by day 4 in early spawns and at a much later developmental stage in late spawns. The differences detected in marker effect among crosses and between spawns of the same cross indicate that complex mechanisms are involved. DNA markers linked to genes with deleterious alleles can aid in identification and elimination of those alleles from inbred lines of
O. aureus.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><doi>10.1016/S0044-8486(01)00727-X</doi><tpages>14</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0044-8486 |
| ispartof | Aquaculture, 2002-04, Vol.206 (3), p.151-164 |
| issn | 0044-8486 1873-5622 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_18307931 |
| source | ScienceDirect Freedom Collection |
| subjects | Animal aquaculture Animal productions Animals Aquaculture Biological and medical sciences Classical genetics, quantitative genetics, hybrids Deleterious genes DNA markers fish culture Freshwater Fundamental and applied biological sciences. Psychology Genes Genetics of eukaryotes. Biological and molecular evolution Genomics Gynogenesis Oreochromis aureus Pisciculture Tilapia Vertebrata Vertebrate aquaculture |
| title | Detection of genes with deleterious alleles in an inbred line of tilapia ( Oreochromis aureus) |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T04%3A15%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Detection%20of%20genes%20with%20deleterious%20alleles%20in%20an%20inbred%20line%20of%20tilapia%20(%20Oreochromis%20aureus)&rft.jtitle=Aquaculture&rft.au=Palti,%20Y&rft.date=2002-04-22&rft.volume=206&rft.issue=3&rft.spage=151&rft.epage=164&rft.pages=151-164&rft.issn=0044-8486&rft.eissn=1873-5622&rft.coden=AQCLAL&rft_id=info:doi/10.1016/S0044-8486(01)00727-X&rft_dat=%3Cproquest_cross%3E18307931%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c395t-96782487bcd04459089e4fd659f6fe5b1314d004d7e658e84e3b500aed6d50e93%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=204689888&rft_id=info:pmid/&rfr_iscdi=true |