Preoperative intraocular pressure as a predictor of selective laser trabeculoplasty efficacy

Purpose To identify predictors of intraocular pressure (IOP) reduction following selective laser trabeculoplasty (SLT) in patients with high‐ and low‐pressure primary open‐angle glaucoma, who are already taking maximally tolerated IOP‐lowering medication and need further IOP reduction. Methods In th...

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Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2016-11, Vol.94 (7), p.692-696
Main Authors: Pillunat, Karin R., Spoerl, Eberhard, Elfes, Greta, Pillunat, Lutz E.
Format: Article
Language:English
Subjects:
Aged
Corneal Pachymetry
Female
Glaucoma, Open-Angle - physiopathology
Glaucoma, Open-Angle - surgery
Humans
Intraocular Pressure - physiology
Laser Therapy
Male
maximum tolerated therapy
Middle Aged
open‐angle glaucoma
Ophthalmology
predictors for success
Preoperative Period
pre‐SLT IOP
Prospective Studies
selective laser trabeculoplasty
Tonometry, Ocular
Trabeculectomy
Treatment Outcome
Visual Acuity - physiology
Visual Fields - physiology
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Summary:Purpose To identify predictors of intraocular pressure (IOP) reduction following selective laser trabeculoplasty (SLT) in patients with high‐ and low‐pressure primary open‐angle glaucoma, who are already taking maximally tolerated IOP‐lowering medication and need further IOP reduction. Methods In this prospective interventional case series, 157 eyes of 157 open‐angle glaucoma patients who were assigned for SLT for further IOP reduction were included. Each patient had diurnal IOP measurements taken before and on average 6 months following SLT. The mean of six IOP measurements was compared. The following parameters were analysed for their association with SLT success: age, gender, spherical equivalent, high‐pressure or normal‐pressure open‐angle glaucoma, number and type of pressure‐lowering medications, lens status, pre‐SLT IOP, IOP at the time of diagnosis, duration of glaucoma, visual field stage and central corneal thickness. Results The only parameter that was predictive for absolute and relative mean diurnal IOP reduction after SLT was the preoperative mean diurnal IOP. One hundred per cent of the patients with a mean diurnal preoperative IOP of more than 18 mmHg had an IOP reduction after SLT. With mean diurnal preoperative values of 14–18 mmHg, 83.1% of the patients, and with values below 14 mmHg only 64% of the patients, showed an IOP reduction. This difference was statistically significant (>18 compared to 14–18: p = 0.002; >18 compared to
ISSN:1755-375X
1755-3768
DOI:10.1111/aos.13094