Healing of BoneCeramic super((TM)) at buccal dehiscence defects at implants installed immediately into extraction sockets. An experimental study in dogs

• Published in: Clinical oral implants research 2016-11, Vol.27 (11), p.1462-1468
• Main Authors: De Santis, Enzo, Lang, Niklaus P, Salata, Luiz A, Pereira, Flavia P, Favero, Vittorio, Botticelli, Daniele
• Format: Article
• Language: English
• ISSN: 0905-7161; 1600-0501
• DOI: 10.1111/clr.12765

Objective To assess the healing outcomes at buccal dehiscence defects after 4 months following implant placement immediately into extraction sockets (IPIES) and filled with a mixture of synthetic hydroxyl apatite (HA) 60% and beta -tri-calcium phosphate ( beta -TCP) 40% in comparison with leaving a blood clot. Material and methods Eight Labrador dogs were used, and an implant was placed immediately following tooth extraction into the distal alveolus of the third premolars, bilaterally. Standardized buccal defects, 8 mm in depth and 4 mm in width at the coronal and 2 mm in width at the apical outlines were created. A mixture of synthetic HA 60% and beta -TCP 40% was used to fill the defects at the test sites, while the control sites were left unfilled. Collagen membranes were used to cover the defects at both sides, and a non-submerged healing was allowed. After 4 months of healing, biopsies were obtained and processed for morphometric analysis. Results A vertical gain in the extent of the bony crest and of osseointegration levels of 4.2 plus or minus 2.4 and 3.3 plus or minus 2.1 mm at the test sites and of 5.0 plus or minus 0.8 and 4.6 plus or minus 1.0 mm at the control sites, respectively, were observed. BIC% within the buccal defects reached similar levels (37-42%) both at test and control sites. None of the means of the variables differed significantly between the two groups. New bone formation within the defects was higher, and the percentage of the connective tissue was lower at the control (65.7 plus or minus 11.7% and 2.5 plus or minus 3.3%, respectively) compared to the test sites (16.8 plus or minus 11.3% and 48.9 plus or minus 29.5%, respectively). These differences were statistically significant. Conclusions The use of a mixture of synthetic HA 60% and beta -TCP 40% to fill surgically created buccal dehiscence defects at IPIES sites covered with a collagen membrane did not improve osseointegration in the defect area.