Probiotics and the Prevention of Antibiotic-Associated Diarrhea in Infants and Children

CLINICAL QUESTION: In children prescribed an antibiotic, is the co-administration of a probiotic associated with lower rates of antibiotic-associated diarrhea without an increase in clinically important adverse events? BOTTOM LINE: Moderate-quality evidence suggests that probiotics are associated wi...

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Bibliographic Details
Published in:JAMA : the journal of the American Medical Association 2016-10, Vol.316 (14), p.1484-1485
Main Authors: Johnston, Bradley C, Goldenberg, Joshua Z, Parkin, Patricia C
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
Child
Childrens health
Diarrhea
Diarrhea - chemically induced
Humans
Infant
Probiotics
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Summary:CLINICAL QUESTION: In children prescribed an antibiotic, is the co-administration of a probiotic associated with lower rates of antibiotic-associated diarrhea without an increase in clinically important adverse events? BOTTOM LINE: Moderate-quality evidence suggests that probiotics are associated with lower rates of antibiotic-associated diarrhea in children (aged 1 month to 18 years) without an increase in adverse events.
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.2016.11838