Manometric Changes of the Lower Esophageal Sphincter After Sleeve Gastrectomy in Obese Patients

Introduction Laparoscopic sleeve gastrectomy has been accepted as an option for surgical treatment of obesity. After surgery, some patients present reflux symptoms associated with endoscopic esophagitis, therefore PPI’s treatment must be indicated. Purpose This study aims to evaluate the manometric...

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Bibliographic Details
Published in:Obesity surgery 2010-03, Vol.20 (3), p.357-362
Main Authors: Braghetto, Italo, Lanzarini, Enrique, Korn, Owen, Valladares, Héctor, Molina, Juan Carlos, Henriquez, Ana
Format: Article
Language:English
Subjects:
Adult
Body Mass Index
Clinical outcomes
Clinical Report
Esophageal pH Monitoring
Esophageal Sphincter, Lower - physiology
Esophageal Sphincter, Lower - physiopathology
Esophagitis - drug therapy
Esophagitis - etiology
Esophagogastric Junction - anatomy & histology
Esophagogastric Junction - physiology
Esophagoscopy
Female
Gastrectomy - adverse effects
Gastroesophageal reflux
Gastroesophageal Reflux - drug therapy
Gastroesophageal Reflux - etiology
Gastrointestinal surgery
Humans
Laparoscopy
Male
Manometry
Medicine
Medicine & Public Health
Obesity
Obesity - complications
Obesity - surgery
Prospective Studies
Proton Pump Inhibitors - therapeutic use
Surgery
Surgical techniques
Treatment Outcome
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Summary:Introduction Laparoscopic sleeve gastrectomy has been accepted as an option for surgical treatment of obesity. After surgery, some patients present reflux symptoms associated with endoscopic esophagitis, therefore PPI’s treatment must be indicated. Purpose This study aims to evaluate the manometric characteristic of the lower esophageal sphincter (LES) before and after sleeve gastrectomy Material and Method This prospective study includes 20 patients submitted to esophageal manometry in order to determine the resting pressure, and total and abdominal LES length before and after the sleeve gastrectomy. Statistical variations on the LESP were validated according to Student’s “ t ” test. Results Seventeen female and three male patients were included, with a mean age of 37.6 ± 12.6 years. All patients reduced their body weight, from an initial BMI of 38.3 kg/m 2 to 28.2 kg/m 2 6 months after surgery. No postoperative complications were observed in these patients. Preoperative mean LESP was 14.2 ± 5.8 mmHg. Postoperative manometry decreased in 17/20 (85%), with a mean value of 11.2 ± 5.7 mmHg ( p  = 0.01). Seven of them presented LESP
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-009-0040-3