Reducing the Rate of Surgical Site Infections After Breast Surgery With the Use of Larger Volumes of 4% Chlorhexidine Gluconate Solution as Preoperative Antiseptic Showering

Surgical site infections (SSIs) increase morbidity and mortality in patients and contribute to significant clinical and economic burden.1,2 Breast surgery has one of the highest SSI rates (2.8%–38.3%) especially in patients undergoing mastectomies.2–4 Recommendations for SSI prevention practices inc...

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Bibliographic Details
Published in:Infection control and hospital epidemiology 2017-03, Vol.38 (3), p.373-375
Main Authors: Persichino, Jon, Lee, Hayley, Sutjita, Made, Talavera, Karla, San-Agustin, Glenn, Gnass, Silvia
Format: Article
Language:English
Subjects:
Adult
Anti-Infective Agents, Local - pharmacology
Body mass index
Breast cancer
Breast surgery
California
Chlorhexidine - analogs & derivatives
Chlorhexidine - pharmacology
Female
Humans
Iodine
Mastectomy
Mastectomy - adverse effects
Middle Aged
Nursing
Preoperative Care - methods
Regression analysis
Retrospective Studies
Skin
Surgeons
Surgical site infections
Surgical Wound Infection - epidemiology
Surgical Wound Infection - prevention & control
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Summary:Surgical site infections (SSIs) increase morbidity and mortality in patients and contribute to significant clinical and economic burden.1,2 Breast surgery has one of the highest SSI rates (2.8%–38.3%) especially in patients undergoing mastectomies.2–4 Recommendations for SSI prevention practices include showering or bathing with an antiseptic agent before the operative day.1,5 Preoperative showering with 4% chlorhexidine gluconate has broad antiseptic activities, reduces skin microbial colony counts, and is associated with significantly fewer SSIs compared to iodine.6–8 Exact concentration, volume, and number of applications for optimal chlorhexidine use have not been established.5 At Riverside University Health System Medical Center, breast surgeries had the highest SSI rates (2.1%–8.6%) from January 2011 to June 2014. [...]we were unable to ascertain the compliance rate of using both antiseptic showering regimens of 4% chlorhexidine gluconate before breast surgery. [...]we did not control for the various operative techniques performed by the surgeons.
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2016.293