Ion-molecule reactions of 2-methoxyethanol with some amines, carboxylic acids and amino acids under chemical ionization conditions

• Published in: Rapid communications in mass spectrometry 1999-01, Vol.13 (14), p.1485-1490
• Main Authors: Pakarinen, Jaana M. H., Moisio, Harri, Holopainen, Sanna, Vainiotalo, Pirjo
• Format: Article
• Language: English
• ISSN: 0951-4198; 1097-0231
• DOI: 10.1002/(SICI)1097-0231(19990730)13:14<1485::AID-RCM672>3.0.CO;2-4

2‐Methoxyethanol chemical ionization of amines, carboxylic acids and amino acids has been found to produce numerous adduct ions. The most intense adduct ions for amines are [M + H]+ and [M + 77]+, for carboxylic acids [M + 27]+, [M + 59]+ and [M + 77]+, and for amino acids [M + H]+, [M + 13]+, [M + 27]+ and [M + 77]+. Either the adduct ion [M + H]+ or [M + 77]+ was the most abundant ion found for amino acids. The proton affinities of amino acids are noticed to control the formation of the [M + H]+ and [M + 77]+ ions. The relative abundance of [M + 13]+ and [M + 27]+ ions varied for different amino acids being most intense for phenylalanine and aspartic acid. Copyright © 1999 John Wiley & Sons, Ltd.