Incidence of Zika Virus Disease by Age and Sex — Puerto Rico, November 1, 2015–October 20, 2016

Zika virus is a flavivirus transmitted primarily by Aedes species mosquitoes; symptoms of infection include rash, arthralgia, fever, and conjunctivitis.* Zika virus infection during pregnancy can cause microcephaly and other serious brain anomalies (1), and in rare cases, Zika virus infection has be...

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Bibliographic Details
Published in:MMWR. Morbidity and mortality weekly report 2016-11, Vol.65 (44), p.1219-1223
Main Authors: Lozier, Matthew, Adams, Laura, Febo, Mitchelle Flores, Torres-Aponte, Jomil, Bello-Pagan, Melissa, Ryff, Kyle R., Munoz-Jordan, Jorge, Garcia, Myriam, Rivera, Aidsa, Read, Jennifer S., Waterman, Stephen H., Sharp, Tyler M., Rivera-Garcia, Brenda
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Child
Child, Preschool
Disease transmission
Female
Guillain-Barre syndrome
Humans
Incidence
Infant
Infection
Male
Middle Aged
Mosquitoes
Pregnancy
Puerto Rico - epidemiology
Sex Distribution
Virus diseases
Young Adult
Zika virus
Zika Virus Infection - epidemiology
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Summary:Zika virus is a flavivirus transmitted primarily by Aedes species mosquitoes; symptoms of infection include rash, arthralgia, fever, and conjunctivitis.* Zika virus infection during pregnancy can cause microcephaly and other serious brain anomalies (1), and in rare cases, Zika virus infection has been associated with Guillain-Barré syndrome (2) and severe thrombocytopenia (3). This report describes the incidence of reported symptomatic Zika virus disease in the U.S. territory of Puerto Rico by age and sex. During November 1, 2015-October 20, 2016, 62,500 suspected Zika virus disease cases were reported to the Puerto Rico Department of Health (PRDH); 29,345 (47%) were confirmed by reverse transcription-polymerase chain reaction (RT-PCR) testing, or were presumptively diagnosed based on serological testing. The highest incidence among confirmed or presumptive cases occurred among persons aged 20-29 years (1,150 cases per 100,000 residents). Among 28,219 (96.2%) nonpregnant patients with confirmed or presumptive Zika virus disease, incidence was higher among women (936 per 100,000 population) than men (576 per 100,000) for all age groups ≥20 years, and the majority (61%) of reported Zika virus disease cases occurred in females. Among suspected Zika virus disease cases in nonpregnant adults aged ≥40 years, the percentage that tested positive among females (52%) was higher than that among males (47%) (p
ISSN:0149-2195
1545-861X
DOI:10.15585/mmwr.mm6544a4