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Impact of pre-admission depression on mortality following myocardial infarction
The prognostic impact of previous depression on myocardial infarction survival remains poorly understood. To examine the association between depression and all-cause mortality following myocardial infarction. Using Danish medical registries, we conducted a nationwide population-based cohort study. W...
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| Published in: | British journal of psychiatry 2017-05, Vol.210 (5), p.356-361 |
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| Main Authors: | , , , , , , |
| Format: | Article |
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| container_end_page | 361 |
| container_issue | 5 |
| container_start_page | 356 |
| container_title | British journal of psychiatry |
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| creator | Sundbøll, Jens Schmidt, Morten Adelborg, Kasper Pedersen, Lars Bøtker, Hans Erik Videbech, Poul Sørensen, Henrik Toft |
| description | The prognostic impact of previous depression on myocardial infarction survival remains poorly understood.
To examine the association between depression and all-cause mortality following myocardial infarction.
Using Danish medical registries, we conducted a nationwide population-based cohort study. We included all patients with first-time myocardial infarction (1995-2014) and identified previous depression as either a depression diagnosis or use of antidepressants. We used Cox regression to compute adjusted mortality rate ratios (aMRRs) with 95% confidence intervals.
We identified 170 771 patients with first-time myocardial infarction. Patients with myocardial infarction and a previous depression diagnosis had higher 19-year mortality risks (87%
78%). The overall aMRR was 1.11 (95% CI 1.07-1.15) increasing to 1.22 (95% CI 1.17-1.27) when including use of antidepressants in the depression definition.
A history of depression was associated with a moderately increased all-cause mortality following myocardial infarction. |
| doi_str_mv | 10.1192/bjp.bp.116.194605 |
| format | article |
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To examine the association between depression and all-cause mortality following myocardial infarction.
Using Danish medical registries, we conducted a nationwide population-based cohort study. We included all patients with first-time myocardial infarction (1995-2014) and identified previous depression as either a depression diagnosis or use of antidepressants. We used Cox regression to compute adjusted mortality rate ratios (aMRRs) with 95% confidence intervals.
We identified 170 771 patients with first-time myocardial infarction. Patients with myocardial infarction and a previous depression diagnosis had higher 19-year mortality risks (87%
78%). The overall aMRR was 1.11 (95% CI 1.07-1.15) increasing to 1.22 (95% CI 1.17-1.27) when including use of antidepressants in the depression definition.
A history of depression was associated with a moderately increased all-cause mortality following myocardial infarction.</description><identifier>ISSN: 0007-1250</identifier><identifier>EISSN: 1472-1465</identifier><identifier>DOI: 10.1192/bjp.bp.116.194605</identifier><identifier>PMID: 28254961</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Antidepressants ; Cardiovascular disease ; Cohort analysis ; Denmark - epidemiology ; Depressive Disorder - complications ; Depressive Disorder - mortality ; Diagnosis ; Female ; Health risk assessment ; Humans ; Kaplan-Meier Estimate ; Male ; Medical diagnosis ; Mental depression ; Middle Aged ; Mortality ; Mortality rates ; Myocardial infarction ; Myocardial Infarction - mortality ; Myocardial Infarction - psychology ; Population studies ; Prognosis ; Prospective Studies ; Psychiatry ; Risk Factors</subject><ispartof>British journal of psychiatry, 2017-05, Vol.210 (5), p.356-361</ispartof><rights>Copyright © Royal College of Psychiatrists, 2017</rights><rights>The Royal College of Psychiatrists 2017.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c416t-b8b38315db561000c0f308ac46d40e9466a42d0cfceea7017f5cf60a6f2107333</citedby><cites>FETCH-LOGICAL-c416t-b8b38315db561000c0f308ac46d40e9466a42d0cfceea7017f5cf60a6f2107333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2315618665/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2315618665?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,12846,21394,21395,27924,27925,30999,33611,33612,34530,34531,43733,44115,72960,74221,74639</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28254961$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sundbøll, Jens</creatorcontrib><creatorcontrib>Schmidt, Morten</creatorcontrib><creatorcontrib>Adelborg, Kasper</creatorcontrib><creatorcontrib>Pedersen, Lars</creatorcontrib><creatorcontrib>Bøtker, Hans Erik</creatorcontrib><creatorcontrib>Videbech, Poul</creatorcontrib><creatorcontrib>Sørensen, Henrik Toft</creatorcontrib><title>Impact of pre-admission depression on mortality following myocardial infarction</title><title>British journal of psychiatry</title><addtitle>Br J Psychiatry</addtitle><description>The prognostic impact of previous depression on myocardial infarction survival remains poorly understood.
To examine the association between depression and all-cause mortality following myocardial infarction.
Using Danish medical registries, we conducted a nationwide population-based cohort study. We included all patients with first-time myocardial infarction (1995-2014) and identified previous depression as either a depression diagnosis or use of antidepressants. We used Cox regression to compute adjusted mortality rate ratios (aMRRs) with 95% confidence intervals.
We identified 170 771 patients with first-time myocardial infarction. Patients with myocardial infarction and a previous depression diagnosis had higher 19-year mortality risks (87%
78%). The overall aMRR was 1.11 (95% CI 1.07-1.15) increasing to 1.22 (95% CI 1.17-1.27) when including use of antidepressants in the depression definition.
A history of depression was associated with a moderately increased all-cause mortality following myocardial infarction.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antidepressants</subject><subject>Cardiovascular disease</subject><subject>Cohort analysis</subject><subject>Denmark - epidemiology</subject><subject>Depressive Disorder - complications</subject><subject>Depressive Disorder - mortality</subject><subject>Diagnosis</subject><subject>Female</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Kaplan-Meier Estimate</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Mortality rates</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - mortality</subject><subject>Myocardial Infarction - psychology</subject><subject>Population studies</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Psychiatry</subject><subject>Risk Factors</subject><issn>0007-1250</issn><issn>1472-1465</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><sourceid>ALSLI</sourceid><sourceid>HEHIP</sourceid><sourceid>M2R</sourceid><sourceid>M2S</sourceid><recordid>eNp1kF1LwzAYhYMobk5_gDdS8Mabzrz5ancpw4_BYDd6HdI0GRltU5MW2b83sqkgCIGcF5735OQgdA14DrAg99Wun1d90mIOCyYwP0FTYAXJgQl-iqYY4yIHwvEEXcS4SyNlpDhHE1ISzhYCpmizanulh8zbrA8mV3XrYnS-y2qT5oNMp_VhUI0b9pn1TeM_XLfN2r3XKtRONZnrrAp6SPAlOrOqiebqeM_Q29Pj6_IlX2-eV8uHda4ZiCGvyoqWFHhdcQEpl8aW4lJpJmqGTfqLUIzUWFttjCowFJZrK7ASlgAuKKUzdHfw7YN_H00cZAquTdOozvgxSigLxhjwUiT09g-682PoUjpJUgQBpRA8UXCgdPAxBmNlH1yrwl4Cll9ty9S2rPqkhTy0nXZujs5j1Zr6Z-O73gTQo6lqq-Dqrfl9-3_bTz9TjII</recordid><startdate>201705</startdate><enddate>201705</enddate><creator>Sundbøll, Jens</creator><creator>Schmidt, Morten</creator><creator>Adelborg, Kasper</creator><creator>Pedersen, Lars</creator><creator>Bøtker, Hans Erik</creator><creator>Videbech, Poul</creator><creator>Sørensen, Henrik Toft</creator><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7TK</scope><scope>7XB</scope><scope>88G</scope><scope>88J</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>M2M</scope><scope>M2O</scope><scope>M2R</scope><scope>M2S</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>201705</creationdate><title>Impact of pre-admission depression on mortality following myocardial infarction</title><author>Sundbøll, Jens ; 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To examine the association between depression and all-cause mortality following myocardial infarction.
Using Danish medical registries, we conducted a nationwide population-based cohort study. We included all patients with first-time myocardial infarction (1995-2014) and identified previous depression as either a depression diagnosis or use of antidepressants. We used Cox regression to compute adjusted mortality rate ratios (aMRRs) with 95% confidence intervals.
We identified 170 771 patients with first-time myocardial infarction. Patients with myocardial infarction and a previous depression diagnosis had higher 19-year mortality risks (87%
78%). The overall aMRR was 1.11 (95% CI 1.07-1.15) increasing to 1.22 (95% CI 1.17-1.27) when including use of antidepressants in the depression definition.
A history of depression was associated with a moderately increased all-cause mortality following myocardial infarction.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>28254961</pmid><doi>10.1192/bjp.bp.116.194605</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | British journal of psychiatry, 2017-05, Vol.210 (5), p.356-361 |
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| source | Applied Social Sciences Index & Abstracts (ASSIA); Cambridge Journals Online; Social Science Premium Collection; Sociology Collection |
| subjects | Adult Aged Aged, 80 and over Antidepressants Cardiovascular disease Cohort analysis Denmark - epidemiology Depressive Disorder - complications Depressive Disorder - mortality Diagnosis Female Health risk assessment Humans Kaplan-Meier Estimate Male Medical diagnosis Mental depression Middle Aged Mortality Mortality rates Myocardial infarction Myocardial Infarction - mortality Myocardial Infarction - psychology Population studies Prognosis Prospective Studies Psychiatry Risk Factors |
| title | Impact of pre-admission depression on mortality following myocardial infarction |
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