Prognostic value of ankle brachial index for future incident heart failure in patients without previous heart failure: data from the impressive predictive value of ankle brachial index for clinical long term outcome in patients with cardiovascular disease examined by ABI study

The ankle brachial index (ABI) is regarded as a predictor of future cardiovascular events. However, the relationship between ABI and incident heart failure (HF) in patients without previous HF is poorly understood. This study aimed to assess the prognostic value of ABI for incident HF in patients wi...

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Bibliographic Details
Published in:Heart and vessels 2017-03, Vol.32 (3), p.295-302
Main Authors: Nishimura, Hitoshi, Miura, Takashi, Minamisawa, Masatoshi, Ueki, Yasushi, Abe, Naoyuki, Hashizume, Naoto, Mochidome, Tomoaki, Harada, Mikiko, Shimizu, Kunihiko, Shoin, Wataru, Yoshie, Koji, Oguchi, Yasutaka, Ebisawa, Soichiro, Motoki, Hirohiko, Izawa, Atsushi, Koyama, Jun, Ikeda, Uichi
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Ankle Brachial Index
Biomedical Engineering and Bioengineering
Cardiac Surgery
Cardiology
Echocardiography
Female
Follow-Up Studies
Heart Failure - diagnostic imaging
Heart Failure - mortality
Hospitalization
Humans
Incidence
Japan
Kaplan-Meier Estimate
Male
Medicine
Medicine & Public Health
Middle Aged
Multivariate Analysis
Original Article
Peripheral Arterial Disease - epidemiology
Predictive Value of Tests
Prognosis
Proportional Hazards Models
Retrospective Studies
Risk Assessment - methods
Risk Factors
Vascular Surgery
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Summary:The ankle brachial index (ABI) is regarded as a predictor of future cardiovascular events. However, the relationship between ABI and incident heart failure (HF) in patients without previous HF is poorly understood. This study aimed to assess the prognostic value of ABI for incident HF in patients without previous HF. The IMPACT–ABI study was a retrospective, single-center, cohort study that enrolled and measured ABI in 3131 patients hospitalized for cardiovascular disease between January 2005 and December 2012. From this cohort, 307 patients were excluded because of previous HF and high (>1.4) ABI. The remaining 2824 patients were stratified into three groups: low ABI (≤0.9), borderline ABI (0.91–0.99), and normal ABI (1.0–1.4). The primary endpoint was hospitalization for HF. Over a mean 4.8-year follow-up, 105 cases of HF occurred. The cumulative incidence of HF was significantly higher in patients with low and borderline ABIs than in those with normal ABI (19.3 vs. 21.0 vs. 10.4 %, log rank P  
ISSN:0910-8327
1615-2573
DOI:10.1007/s00380-016-0873-3