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Fungemia due to Saprochaete capitata in a non-neutropenic patient hospitalized in an intensive care unit after cardiac surgery

The majority of invasive fungal infections observed in non-neutropenic patients hospitalized in an intensive care unit are caused by Candida spp and current guidelines recommend echinocandins as the first-line treatment. Fungemias caused by filamentous or arthrosporic fungi such as Saprochaete capit...

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Published in:Journal de mycologie médicale 2017-06, Vol.27 (2), p.281-284
Main Authors: Cavanna, C., Lallitto, F., Mangione, F., Tamarozzi, F., Marone, P., Ceriana, P.
Format: Article
Language:English
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Summary:The majority of invasive fungal infections observed in non-neutropenic patients hospitalized in an intensive care unit are caused by Candida spp and current guidelines recommend echinocandins as the first-line treatment. Fungemias caused by filamentous or arthrosporic fungi such as Saprochaete capitata (previously named Geotrichum capitatum) are extremely rare. In fact, invasive infections due to S. capitata have been reported almost exclusively in neutropenic oncohematological patients. In this report, we describe a case of fungemia caused by S. capitata in a non-neutropenic patient hospitalized in an intensive care unit after aortic valve replacement. The prompt identification of S. capitata is extremely important because of its intrinsic resistance to echinocandins. Les infections fongiques invasives chez les patients non neutropéniques hospitalisés en unité de soins intensifs sont causées principalement par des levures du genre Candida et les guidelines recommandent une échinocandine en traitement de première ligne. Les fongémies causées par des champignons filamenteux ou arthrosporés tels que Saprochaete capitata (anciennement Geotrichum capitatum) sont extrêmement rares. En fait, les infections invasives dues à S. capitata ont été reportées presque exclusivement chez des patients neutropéniques d’oncohématologie. Dans cette étude, nous décrivons un cas de fongémie causée par S. capitata chez un patient non neutropénique hospitalisé en soins intensifs après remplacement de valve aortique. L’identification rapide de S. capitata est très importante du fait de sa résistance intrinsèque aux échinocandines.
ISSN:1156-5233
1773-0449
DOI:10.1016/j.mycmed.2017.01.014