Association of physical activity with glycaemic control and cardiovascular risk profile in 65 666 people with Type 2 diabetes from Germany and Austria

• Published in: Diabetic medicine 2014-08, Vol.31 (8), p.905-912
• Main Authors: Hermann, G., Herbst, A., Schütt, M., Kempe, H.-P., Krakow, D., Müller-Korbsch, M., Holl, R. W.
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Austria - epidemiology; Biological and medical sciences; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - etiology; Cardiovascular Diseases - prevention & control; Combined Modality Therapy; Diabetes; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - physiopathology; Diabetes Mellitus, Type 2 - therapy; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; Germany - epidemiology; Glycated Hemoglobin A - analysis; Humans; Hyperglycemia - prevention & control; Hypoglycemic Agents - therapeutic use; Male; Medical sciences; Middle Aged; Motor Activity; Population Surveillance; Prospective Studies; Registries; Risk Factors; Sex Factors; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Vertebrates: endocrinology; Young Adult
• ISSN: 0742-3071; 1464-5491
• DOI: 10.1111/dme.12438

Aims To provide representative data from routine diabetes care concerning the physical activity levels of people with Type 2 diabetes, and to show the association of activity level with cardio‐metabolic risk profile in a gender‐specific analysis. Methods The anonymized data from 65 666 subjects with Type 2 diabetes, who have been receiving treatment in specialized diabetes institutions, were analysed using a large multi‐centre database. The population was categorized as physically inactive (PA0), active 1–2 times per week (PA1), active >2 times per week (PA2), and then stratified by age (20–59 and 60–80 years). BMI, glycaemic control (measured by HbA1c levels), blood pressure, lipid profile and therapeutic regimen were adjusted for age, gender and diabetes duration. Results Most subjects were inactive (PA0: 90%; PA1: 6%, PA2: 4%). BMI, HbA1c and lipid profiles were better in older subjects and hypertension rates were lower in younger subjects. In both age groups, BMI, HbA1c (both P