Building Capability for Clinical Pharmacology Research in Sub‐Saharan Africa

A strong scientific rationale exists for conducting clinical pharmacology studies in target populations because local factors such as genetics, environment, comorbidities, and diet can affect variability in drug responses. However, clinical pharmacology studies are not widely conducted in sub‐Sahara...

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Bibliographic Details
Published in:Clinical pharmacology and therapeutics 2017-11, Vol.102 (5), p.786-795
Main Authors: Gutierrez, MM, Pillai, G, Felix, S, Romero, F, Onyango, KO, Owusu‐Agyei, S, Asante, KP, Barnes, KI, Sinxadi, P, Allen, E, Abdulla, S, Masimirembwa, C, Munyoro, M, Yimer, G, Gebre‐Mariam, T, Spector, J, Ogutu, B
Format: Article
Language:English
Subjects:
Africa South of the Sahara - epidemiology
Biomedical Research - methods
Biomedical Research - trends
Clinical Trials as Topic - methods
Humans
International Cooperation
Pharmacogenetics - methods
Pharmacogenetics - trends
Pharmacology, Clinical - methods
Pharmacology, Clinical - trends
Public-Private Sector Partnerships - trends
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Summary:A strong scientific rationale exists for conducting clinical pharmacology studies in target populations because local factors such as genetics, environment, comorbidities, and diet can affect variability in drug responses. However, clinical pharmacology studies are not widely conducted in sub‐Saharan Africa, in part due to limitations in technical expertise and infrastructure. Since 2012, a novel public‐private partnership model involving research institutions and a pharmaceutical company has been applied to developing increased capability for clinical pharmacology research in multiple African countries.
ISSN:0009-9236
1532-6535
DOI:10.1002/cpt.695