Preventing, treating, and predicting barbering: A fundamental role for biomarkers of oxidative stress in a mouse model of Trichotillomania

Barbering, where a "barber" mouse plucks hair from its cagemates or itself, is both a spontaneously occurring abnormal behavior in mice and a well validated model of Trichotillomania (TTM). N-Acetylcysteine, (NAC) a cysteine derived food additive, is remarkably effective in treating TTM pa...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2017-04, Vol.12 (4), p.e0175222
Main Authors: Vieira, Giovana de L. T., Lossie, Amy C., Lay, Donald C., Radcliffe, John S., Garner, Joseph P.
Format: Article
Language:English
Subjects:
8-Hydroxydeoxyguanosine
Acetylcysteine
Acetylcysteine - therapeutic use
Animal sciences
Animals
Antioxidants
Behavior
Biology and Life Sciences
Biomarkers
Biomarkers - metabolism
Brain
Brain research
Curing
Damage prevention
Deoxyguanosine
Deoxyguanosine - analogs & derivatives
Deoxyguanosine - metabolism
Deoxyguanosine - urine
Deoxyribonucleic acid
Dermatitis
Disease Models, Animal
DNA
Enzymes
Food additives
Free radicals
Glutathione
Grooming
Hair
Hypertension
Mathematical models
Medicine and Health Sciences
Metabolism
Mice
Mice, Inbred C57BL
Obsessive compulsive disorder
Oxidative Stress
Oxygen
Pathogenesis
Psychiatry
Reactive oxygen species
Rodents
Schizophrenia
Trichotillomania - drug therapy
Trichotillomania - metabolism
Urine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!