Impact of Obesity and Nonobesity on Grading the Severity of Aortic Valve Stenosis

We tested the hypothesis that the disproportionate increase of body surface area in obesity may lead to the overestimation of aortic stenosis (AS) severity when the aortic valve area (AVA) is indexed (AVAI) for body surface area in 1,524 patients enrolled in the Simvastatin and Ezetimibe in AS study...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of cardiology 2014-05, Vol.113 (9), p.1532-1535
Main Authors: Rogge, Barbara P., MD, Gerdts, Eva, MD, PhD, Cramariuc, Dana, MD, PhD, Bahlmann, Edda, MD, Jander, Nikolaus, MD, Gohlke-Bärwolf, Christa, MD, Pedersen, Terje R., MD, PhD, Lønnebakken, Mai Tone, MD, PhD
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aortic Valve Stenosis - complications
Aortic Valve Stenosis - diagnosis
Aortic Valve Stenosis - diagnostic imaging
Body mass index
Cardiology
Cardiovascular
Confidence intervals
Echocardiography
Female
Heart attacks
Heart failure
Hospitalization
Humans
Hypertension
Lipids
Male
Middle Aged
Mortality
Obesity
Obesity - complications
Population
Regression Analysis
Severity of Illness Index
Sinuses
Stroke
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We tested the hypothesis that the disproportionate increase of body surface area in obesity may lead to the overestimation of aortic stenosis (AS) severity when the aortic valve area (AVA) is indexed (AVAI) for body surface area in 1,524 patients enrolled in the Simvastatin and Ezetimibe in AS study. Obesity was defined as a body mass index of ≥30 kg/m2 . Peak aortic jet velocity, mean aortic gradient, AVA, and energy loss (EL) did not differ, although AVAI and EL indexed (ELI) for body surface area were significantly smaller in the obese group (n = 321) compared with the nonobese (n = 1,203) group (both p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2014.01.429