How effectors promote beneficial interactions

• Published in: Current opinion in plant biology 2017-08, Vol.38, p.148-154
• Main Authors: Miwa, Hiroki, Okazaki, Shin
• Format: Article
• Language: English
• Subjects: Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Gene Expression Regulation, Plant; Plant Proteins - genetics; Plant Proteins - metabolism; Plant Root Nodulation - genetics; Plant Root Nodulation - physiology; Plant Roots - metabolism; Plant Roots - microbiology; Rhizobium - genetics; Rhizobium - physiology; Symbiosis - genetics; Symbiosis - physiology
• ISSN: 1369-5266; 1879-0356
• DOI: 10.1016/j.pbi.2017.05.011

•Beneficial microbes modulate host-signaling pathways using effectors.•Rhizobia use the similar effectors as pathogenic bacteria to suppress host defenses.•Rhizobial effectors can hijack leguminous nodulation signaling. Beneficial microbes such as rhizobia possess effector proteins that are secreted into the host cytoplasm where they modulate host-signaling pathways. Among these effectors, type 3 secreted effectors (T3Es) of rhizobia play roles in promoting nitrogen-fixing nodule symbiosis, suppressing host defenses and directly activating symbiosis-related processes. Rhizobia use the same strategy as pathogenic bacteria to suppress host defenses such as targeting the MAPK cascade. In addition, rhizobial T3E can promote root nodule symbiosis by directly activating Nod factor signaling, which bypasses Nod factor perception. The various strategies employed by beneficial microbes to promote infection and maintain viability in the host are therefore crucial for plant endosymbiosis.