Incidence and prognostic implications of late bleeding after myocardial infarction or unstable angina according to treatment strategy

Abstract Background Bleeding complications accompanying coronary revascularization are associated with increased mortality; however, little data is available on subsequent bleeding risk. We used administrative data to assess the incidence of late bleeding events in patients with acute coronary syndr...

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Bibliographic Details
Published in:Canadian journal of cardiology 2017-08, Vol.33 (8), p.998-1005
Main Authors: Brinkert, M., MD, Southern, D.A., MSc, James, M.T., MD PhD, Knudtson, M.L., MD, Anderson, T.J., MD, Charbonneau, F., MD MSc
Format: Article
Language:English
Subjects:
Aged
Alberta - epidemiology
Angina, Unstable - surgery
Cardiovascular
Cause of Death - trends
Coronary Artery Bypass - adverse effects
Coronary Artery Bypass - standards
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Myocardial Infarction - surgery
Patient Readmission - trends
Percutaneous Coronary Intervention - adverse effects
Percutaneous Coronary Intervention - standards
Postoperative Hemorrhage - epidemiology
Postoperative Hemorrhage - etiology
Practice Guidelines as Topic
Retrospective Studies
Survival Rate - trends
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Summary:Abstract Background Bleeding complications accompanying coronary revascularization are associated with increased mortality; however, little data is available on subsequent bleeding risk. We used administrative data to assess the incidence of late bleeding events in patients with acute coronary syndrome (ACS) according to treatment allocation. Methods The cohort and bleeding events were identified through Canadian Institute for Health Information discharge abstract database. Crude and adjusted odds ratios (OR) were calculated for index and post-index admission bleeding up to one year after discharge. Results Out of 31.941 patients hospitalized with ACS, 7.681 (32.4%) patients were treated with medication alone, 3.728 (15.2%) received an angiogram without intervention and 13.075 (53.4%) received PCI or CABG. The overall incidence of readmission with bleeding based on administrative codes was low (3.8% for medically treated patients, 2.8% for angiogram only patients, 2.6% for CABG patients and 1.8% for PCI patients, p
ISSN:0828-282X
1916-7075
DOI:10.1016/j.cjca.2017.05.001