Impact of Cirrhosis in Patients Who Underwent Surgical Aortic Valve Replacement

Cirrhosis is known to adversely affect cardiac surgery outcomes. Our objective was to quantify the morbidity, mortality, and cost that cirrhosis adds to surgical aortic valve replacement. From 1998 to 2011, 423,789 patients in the Nationwide Inpatient Sample Healthcare Cost Utilization Project under...

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Bibliographic Details
Published in:The American journal of cardiology 2017-08, Vol.120 (4), p.648-654
Main Authors: Steffen, Robert J., Bakaeen, Faisal G., Vargo, Patrick R., Kindzelski, Bogdan A., Johnston, Douglas R., Roselli, Eric E., Gillinov, A. Marc, Svensson, Lars G., Soltesz, Edward G.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Algorithms
Aortic valve
Aortic Valve Stenosis - complications
Aortic Valve Stenosis - mortality
Aortic Valve Stenosis - surgery
Blood transfusion
Cause of Death - trends
Circulation
Cirrhosis
Congestive heart failure
Coronary vessels
Death
Demographics
Disorders
Female
Government programs
Health care
Heart
Heart surgery
Heart Valve Prosthesis Implantation
Hospital Mortality - trends
Humans
Incidence
Kidneys
Liver cirrhosis
Liver Cirrhosis - complications
Liver Cirrhosis - epidemiology
Male
Middle Aged
Morbidity
Mortality
Patients
Pneumonia
Propensity Score
Pulmonary circulation
Renal failure
Retrospective Studies
Risk analysis
Risk Assessment
Risk Factors
Stroke
Surgery
Survival Rate - trends
Thoracic surgery
Transfusion
United States - epidemiology
Weight loss
Wound infection
Young Adult
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Summary:Cirrhosis is known to adversely affect cardiac surgery outcomes. Our objective was to quantify the morbidity, mortality, and cost that cirrhosis adds to surgical aortic valve replacement. From 1998 to 2011, 423,789 patients in the Nationwide Inpatient Sample Healthcare Cost Utilization Project underwent isolated aortic valve replacement; 2,769 (0.7%) had cirrhosis. Multivariable linear regression and 1:1 propensity matching were used to determine the effect of cirrhosis on postsurgical outcomes. The number of patients with cirrhosis who underwent surgical aortic valve replacement per year more than tripled during the 13-year study period. Patients with cirrhosis were more likely to be younger (p 
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2017.05.034