"On demand" redox buffering by H2S contributes to antibiotic resistance revealed by a bacteria-specific H2S donor

Understanding the mechanisms of antimicrobial resistance (AMR) will help launch a counter-offensive against human pathogens that threaten our ability to effectively treat common infections. Herein, we report bis(4-nitrobenzyl)sulfanes, which are activated by a bacterial enzyme to produce hydrogen su...

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Bibliographic Details
Published in:Chemical science (Cambridge) 2017-07, Vol.8 (7), p.4967-4972
Main Authors: Shukla, Prashant, Khodade, Vinayak S, SharathChandra, Mallojjala, Chauhan, Preeti, Mishra, Saurabh, Siddaramappa, Shivakumara, Pradeep, Bulagonda Eswarappa, Singh, Amit, Chakrapani, Harinath
Format: Article
Language:English
Subjects:
Activation
Antibiotics
Bacteria
Chemistry
Demand
Drugs
Enzymes
Escherichia coli
Launches
Psychological effects
Online Access:Get full text
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