Initial experience of transcatheter closure of subarterial VSD with the Amplatzer duct occluder

The traditional treatment of subarterial ventricular septal defect (VSD) is open heart surgery. This study aimed to evaluate the feasibility, safety and outcome of transcatheter closure with the Amplatzer duct occluder (ADO). Between March 2012 and June 2015, a total of 16 patients (8 male and 8 fem...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the Chinese Medical Association 2017-08, Vol.80 (8), p.487-491
Main Authors: Shyu, Tsung-Cheng, Lin, Ming-Chih, Quek, Yeak-Wun, Lin, Sheng-Je, Saw, Hean-Pat, Jan, Sheng-Ling, Fu, Yun-Ching
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Amplatzer duct occluder
Cardiac Catheterization
Child
Child, Preschool
Doubly committed
Female
Heart Septal Defects, Ventricular - surgery
Humans
Male
Middle Aged
Retrospective Studies
Septal Occluder Device - adverse effects
Subarterial
Transcatheter closure
Ventricular septal defect
Young Adult
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The traditional treatment of subarterial ventricular septal defect (VSD) is open heart surgery. This study aimed to evaluate the feasibility, safety and outcome of transcatheter closure with the Amplatzer duct occluder (ADO). Between March 2012 and June 2015, a total of 16 patients (8 male and 8 female) with subarterial VSD who underwent transcatheter closure with the ADO were enrolled retrospectively. Their age ranged from 3.0 to 65.6 years, with the median of 35.6 years; their body weights ranged from 14 to 92 kg with the median of 60 kg. All patients had prolapse of the right coronary cusp without subaortic rim. Mild aortic regurgitation was noted in 11 (69%) patients. Left ventriculogram showed VSD size ranged from 1.3 to 9.3 mm with the median of 3.5 mm. The device was successfully implanted in 88% (14/16) of the patients. Although one patient had mild skin allergy to contrast medium, no other complication was noted. Complete closure rate was 64%, 86%, 86% and 86% at 1-day, 1-month, 6-month and 12-month follow-up, respectively. Two patients developed new or worsening aortic regurgitation during follow-up. Transcatheter closure of subarterial VSD with ADO is technically feasible and safe in patients older than 7 years of age. However, development or worsening of aortic regurgitation requires long-term follow-up.
ISSN:1726-4901
1728-7731
DOI:10.1016/j.jcma.2016.10.015