Prevalence of sleep abnormalities in Indian children with Autism Spectrum Disorder; a cross sectional study

Abstract Background The prevalence of Autism spectrum disorder (ASD) is on rise. Apart from the core behavioral issues of impaired communication and social interaction and restricted and/or repeated behavioral phenotype, comorbidities like sleep problems are increasingly getting recognized as import...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric neurology 2017-09, Vol.74, p.62-67
Main Authors: Aathira, R, Gulati, Sheffali, Tripathi, Manjari, Shukla, Garima, Chakrabarty, Biswaroop, Sapra, Savita, Dang, Nitika, Gupta, Anupama, Kabra, Madhulika, Pandey, R.M
Format: Article
Language:English
Subjects:
ASD
Autism Spectrum Disorder - complications
Autism Spectrum Disorder - epidemiology
Child
Child, Preschool
Cross-Sectional Studies
CSHQ
Female
Follow-Up Studies
Humans
India - epidemiology
Male
Neurology
Pediatrics
Prevalence
PSG
sleep problems
Sleep Wake Disorders - complications
Sleep Wake Disorders - epidemiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Background The prevalence of Autism spectrum disorder (ASD) is on rise. Apart from the core behavioral issues of impaired communication and social interaction and restricted and/or repeated behavioral phenotype, comorbidities like sleep problems are increasingly getting recognized as important determinants of management and overall quality of life. Methods This study was conducted in a tertiary care teaching hospital in north India over a two year period. Children diagnosed with ASD and normally developing children (controls) aged 3 to 10 years were enrolled in the study. Both groups underwent sleep evaluation based on CSHQ (Children’s Sleep Habit Questionnaire). Children with ASD also underwent PSG (Polysomnography), CARS (Childhood Autism Rating Scale), CBCL(Childhood Behavioral Checklist) and DP-3(Developmental Profile-3) assessments. Results The prevalence of poor sleepers among ASD and controls were 77.5% (C.I. 66-86.5). and 29.2% (C.I. 18.6-41.5) respectively (p1. The CBCL score was significantly high in poor sleepers compared to good sleepers on CSHQ (p=0.004). There was no correlation of CARS or DP-3 score with sleep problems in ASD children. Conclusions Nearly three-fourth of ASD children have sleep abnormalities with possible effect on behavioral phenotype. The PSG findings provide further insight with opportunity for pharmacological interventions. Screening for sleep problems is imperative for appropriate management and overall improvement in quality of life in children with ASD.
ISSN:0887-8994
1873-5150
DOI:10.1016/j.pediatrneurol.2017.05.019