Fragrance allergy: assessing the risk from washed fabrics

The prevalence of contact allergy to fragrance ingredients increased during the last part of the 20th century with the consequence that a substantial number of individuals are at risk of experiencing allergic contact dermatitis (ACD) if they have a sufficient degree of skin exposure to the chemical...

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Bibliographic Details
Published in:Contact dermatitis 2006-07, Vol.55 (1), p.48-53
Main Authors: Corea, Namali V., Basketter, David A., Clapp, Catherine, Van Asten, Arian, Marty, Jean-Paul, Pons-Guiraud, Annick, Laverdet, Catherine
Format: Article
Language:English
Subjects:
Allergens
Allergic diseases
Animals
Biological and medical sciences
Consumer Product Safety
Dermatitis, Contact - etiology
Dermatitis, Contact - prevention & control
Domestic and cosmetic products toxicology
Dose-Response Relationship, Immunologic
fabric washing
fragrance allergy
Humans
Immunopathology
induction thresholds
Laundering - methods
Mathematical Computing
Medical sciences
Mice
Models, Animal
Patch Tests
Perfume - adverse effects
Perfume - chemistry
Risk Assessment
Skin allergic diseases. Stinging insect allergies
skin sensitization
Textiles - analysis
Toxicology
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Summary:The prevalence of contact allergy to fragrance ingredients increased during the last part of the 20th century with the consequence that a substantial number of individuals are at risk of experiencing allergic contact dermatitis (ACD) if they have a sufficient degree of skin exposure to the chemical to which they have become sensitized. Such exposure does not necessarily have to arise from the type of source that originally induced the sensitization. A number of sources of exposure are clearly associated with risk of elicitation of ACD, but the role of fragrance deposited on fabrics, for example as a result of laundry processes, also can be questioned. In this article, firstly, the risk of the induction of fragrance‐related ACD from exposure to fragrance via fabric is considered. Using a quantitative risk‐assessment approach, the risk appears to be extremely low. The possibility that fragrance residues on laundered fabrics might elicit reactions in those already sensitized by a different route is also discussed. Clinically, clothing pattern dermatitis associated with fragrance allergy is almost never observed, although this could be investigated clinically by exposing sensitized individuals to the relevant fragrance allergen.
ISSN:0105-1873
1600-0536
DOI:10.1111/j.0105-1873.2006.00872.x