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Urolithiasis is prevalent and associated with reduced bone mineral density in β‐thalassaemia major
Asymptomatic urolithiasis is common and of mixed composition in patients with β‐thalassaemia major. Twenty‐seven subjects were imaged using dual‐energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generall...
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| Published in: | Internal medicine journal 2017-09, Vol.47 (9), p.1064-1067 |
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| Main Authors: | , , , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c3603-e0663f23564a925f0cee2a5663cb4b5f99d5acacb67f9f5aea7a31491c9f6fdd3 |
| container_end_page | 1067 |
| container_issue | 9 |
| container_start_page | 1064 |
| container_title | Internal medicine journal |
| container_volume | 47 |
| creator | Wong, Phillip Milat, Frances Fuller, Peter J. Kerr, Peter G. Doery, James C. G. Oh, Danielle H. Jackson, Dana Gillespie, Matthew T. Bowden, Donald K. Pasricha, Sant‐Rayn Lau, Ken K. |
| description | Asymptomatic urolithiasis is common and of mixed composition in patients with β‐thalassaemia major. Twenty‐seven subjects were imaged using dual‐energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium‐containing urolithiasis was associated with reduced femoral neck Z scores. |
| doi_str_mv | 10.1111/imj.13533 |
| format | article |
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G. ; Oh, Danielle H. ; Jackson, Dana ; Gillespie, Matthew T. ; Bowden, Donald K. ; Pasricha, Sant‐Rayn ; Lau, Ken K.</creator><creatorcontrib>Wong, Phillip ; Milat, Frances ; Fuller, Peter J. ; Kerr, Peter G. ; Doery, James C. G. ; Oh, Danielle H. ; Jackson, Dana ; Gillespie, Matthew T. ; Bowden, Donald K. ; Pasricha, Sant‐Rayn ; Lau, Ken K.</creatorcontrib><description>Asymptomatic urolithiasis is common and of mixed composition in patients with β‐thalassaemia major. Twenty‐seven subjects were imaged using dual‐energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium‐containing urolithiasis was associated with reduced femoral neck Z scores.</description><identifier>ISSN: 1444-0903</identifier><identifier>EISSN: 1445-5994</identifier><identifier>DOI: 10.1111/imj.13533</identifier><identifier>PMID: 28891172</identifier><language>eng</language><publisher>Melbourne: John Wiley & Sons Australia, Ltd</publisher><subject>Adult ; beta-Thalassemia - diagnostic imaging ; beta-Thalassemia - epidemiology ; beta-Thalassemia - metabolism ; Bone Density - physiology ; computed tomography ; Female ; Humans ; Hypercalcemia - diagnostic imaging ; Hypercalcemia - epidemiology ; Hypercalcemia - metabolism ; kidney stone ; Male ; Middle Aged ; osteoporosis ; Prevalence ; thalassaemia ; urolithiasis ; Urolithiasis - diagnostic imaging ; Urolithiasis - epidemiology ; Urolithiasis - metabolism ; Young Adult</subject><ispartof>Internal medicine journal, 2017-09, Vol.47 (9), p.1064-1067</ispartof><rights>2017 Royal Australasian College of Physicians</rights><rights>2017 Royal Australasian College of Physicians.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3603-e0663f23564a925f0cee2a5663cb4b5f99d5acacb67f9f5aea7a31491c9f6fdd3</citedby><cites>FETCH-LOGICAL-c3603-e0663f23564a925f0cee2a5663cb4b5f99d5acacb67f9f5aea7a31491c9f6fdd3</cites><orcidid>0000-0003-1095-0926</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28891172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wong, Phillip</creatorcontrib><creatorcontrib>Milat, Frances</creatorcontrib><creatorcontrib>Fuller, Peter J.</creatorcontrib><creatorcontrib>Kerr, Peter G.</creatorcontrib><creatorcontrib>Doery, James C. G.</creatorcontrib><creatorcontrib>Oh, Danielle H.</creatorcontrib><creatorcontrib>Jackson, Dana</creatorcontrib><creatorcontrib>Gillespie, Matthew T.</creatorcontrib><creatorcontrib>Bowden, Donald K.</creatorcontrib><creatorcontrib>Pasricha, Sant‐Rayn</creatorcontrib><creatorcontrib>Lau, Ken K.</creatorcontrib><title>Urolithiasis is prevalent and associated with reduced bone mineral density in β‐thalassaemia major</title><title>Internal medicine journal</title><addtitle>Intern Med J</addtitle><description>Asymptomatic urolithiasis is common and of mixed composition in patients with β‐thalassaemia major. Twenty‐seven subjects were imaged using dual‐energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium‐containing urolithiasis was associated with reduced femoral neck Z scores.</description><subject>Adult</subject><subject>beta-Thalassemia - diagnostic imaging</subject><subject>beta-Thalassemia - epidemiology</subject><subject>beta-Thalassemia - metabolism</subject><subject>Bone Density - physiology</subject><subject>computed tomography</subject><subject>Female</subject><subject>Humans</subject><subject>Hypercalcemia - diagnostic imaging</subject><subject>Hypercalcemia - epidemiology</subject><subject>Hypercalcemia - metabolism</subject><subject>kidney stone</subject><subject>Male</subject><subject>Middle Aged</subject><subject>osteoporosis</subject><subject>Prevalence</subject><subject>thalassaemia</subject><subject>urolithiasis</subject><subject>Urolithiasis - diagnostic imaging</subject><subject>Urolithiasis - epidemiology</subject><subject>Urolithiasis - metabolism</subject><subject>Young Adult</subject><issn>1444-0903</issn><issn>1445-5994</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp1kEtOwzAQhi0E4r3gAshLWKTYsZ3gJUI8ikBs6DqaOGPhKo9ip1TdcQTOwkE4BCfBNIUd1kieGX3zLX5Cjjgb8fjOXDMdcaGE2CC7XEqVKK3l5qqXCdNM7JC9EKaM8VxouU120vNzzXme7hKc-K52_bOD4AKNNfP4CjW2PYW2ohBCZxz0WNFFpKjHam7iUHYt0sa16KGmFbbB9UvqWvr58fX23j9DHQ8BGwe0gWnnD8iWhTrg4frfJ5Prq6fL2-T-8WZ8eXGfGJExkSDLMmFToTIJOlWWGcQUVFyaUpbKal0pMGDKLLfaKkDIQXCpudE2s1Ul9snJ4J357mWOoS8aFwzWNbTYzUPBtcjzTKqcRfR0QI3vQvBoi5l3DfhlwVnxk2oRUy1WqUb2eK2dlw1Wf-RvjBE4G4CFq3H5v6kYP9wNym__q4Tw</recordid><startdate>201709</startdate><enddate>201709</enddate><creator>Wong, Phillip</creator><creator>Milat, Frances</creator><creator>Fuller, Peter J.</creator><creator>Kerr, Peter G.</creator><creator>Doery, James C. 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G. ; Oh, Danielle H. ; Jackson, Dana ; Gillespie, Matthew T. ; Bowden, Donald K. ; Pasricha, Sant‐Rayn ; Lau, Ken K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3603-e0663f23564a925f0cee2a5663cb4b5f99d5acacb67f9f5aea7a31491c9f6fdd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>beta-Thalassemia - diagnostic imaging</topic><topic>beta-Thalassemia - epidemiology</topic><topic>beta-Thalassemia - metabolism</topic><topic>Bone Density - physiology</topic><topic>computed tomography</topic><topic>Female</topic><topic>Humans</topic><topic>Hypercalcemia - diagnostic imaging</topic><topic>Hypercalcemia - epidemiology</topic><topic>Hypercalcemia - metabolism</topic><topic>kidney stone</topic><topic>Male</topic><topic>Middle Aged</topic><topic>osteoporosis</topic><topic>Prevalence</topic><topic>thalassaemia</topic><topic>urolithiasis</topic><topic>Urolithiasis - diagnostic imaging</topic><topic>Urolithiasis - epidemiology</topic><topic>Urolithiasis - metabolism</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wong, Phillip</creatorcontrib><creatorcontrib>Milat, Frances</creatorcontrib><creatorcontrib>Fuller, Peter J.</creatorcontrib><creatorcontrib>Kerr, Peter G.</creatorcontrib><creatorcontrib>Doery, James C. G.</creatorcontrib><creatorcontrib>Oh, Danielle H.</creatorcontrib><creatorcontrib>Jackson, Dana</creatorcontrib><creatorcontrib>Gillespie, Matthew T.</creatorcontrib><creatorcontrib>Bowden, Donald K.</creatorcontrib><creatorcontrib>Pasricha, Sant‐Rayn</creatorcontrib><creatorcontrib>Lau, Ken K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal medicine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wong, Phillip</au><au>Milat, Frances</au><au>Fuller, Peter J.</au><au>Kerr, Peter G.</au><au>Doery, James C. G.</au><au>Oh, Danielle H.</au><au>Jackson, Dana</au><au>Gillespie, Matthew T.</au><au>Bowden, Donald K.</au><au>Pasricha, Sant‐Rayn</au><au>Lau, Ken K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Urolithiasis is prevalent and associated with reduced bone mineral density in β‐thalassaemia major</atitle><jtitle>Internal medicine journal</jtitle><addtitle>Intern Med J</addtitle><date>2017-09</date><risdate>2017</risdate><volume>47</volume><issue>9</issue><spage>1064</spage><epage>1067</epage><pages>1064-1067</pages><issn>1444-0903</issn><eissn>1445-5994</eissn><abstract>Asymptomatic urolithiasis is common and of mixed composition in patients with β‐thalassaemia major. Twenty‐seven subjects were imaged using dual‐energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium‐containing urolithiasis was associated with reduced femoral neck Z scores.</abstract><cop>Melbourne</cop><pub>John Wiley & Sons Australia, Ltd</pub><pmid>28891172</pmid><doi>10.1111/imj.13533</doi><tpages>1094</tpages><orcidid>https://orcid.org/0000-0003-1095-0926</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Internal medicine journal, 2017-09, Vol.47 (9), p.1064-1067 |
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| language | eng |
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| source | Wiley |
| subjects | Adult beta-Thalassemia - diagnostic imaging beta-Thalassemia - epidemiology beta-Thalassemia - metabolism Bone Density - physiology computed tomography Female Humans Hypercalcemia - diagnostic imaging Hypercalcemia - epidemiology Hypercalcemia - metabolism kidney stone Male Middle Aged osteoporosis Prevalence thalassaemia urolithiasis Urolithiasis - diagnostic imaging Urolithiasis - epidemiology Urolithiasis - metabolism Young Adult |
| title | Urolithiasis is prevalent and associated with reduced bone mineral density in β‐thalassaemia major |
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