Changes in pulmonary artery systolic pressure correlate with radiographic severity and peripheral oxygenation in adults with community‐acquired pneumonia

• Published in: Journal of clinical ultrasound 2018-01, Vol.46 (1), p.41-47
• Main Authors: Sreter, Katherina Bernadette, Budimir, Ivan, Golub, Andrija, Dorosulić, Zdravko, Sabol Pušić, Mateja, Boban, Marko
• Format: Article
• Language: English
• Subjects: Adult; Adults; Aged; Antibiotics; arterial blood gas; Blood gas analysis; Blood pressure; Chronic obstructive pulmonary disease; Cohort Studies; Communities; Community-Acquired Infections - diagnostic imaging; Community-Acquired Infections - physiopathology; community‐acquired pneumonia; Correlation; Doppler effect; Echocardiography; Echocardiography, Doppler; Female; Gas analysis; Heart; Humans; Lung diseases; Male; Middle Aged; Obstructive lung disease; Oxygen - blood; Oxygenation; Partial Pressure; Patients; Peripheral blood; Pneumonia; Pneumonia - blood; Pneumonia - diagnostic imaging; Pneumonia - physiopathology; Prospective Studies; Pulmonary arteries; Pulmonary artery; Pulmonary Artery - diagnostic imaging; Pulmonary Artery - physiopathology; pulmonary artery systolic pressure; respiratory dynamics; Segments; Systolic pressure; Ultrasonic imaging; Ventricle
• ISSN: 0091-2751; 1097-0096
• DOI: 10.1002/jcu.22523

Purpose The aim of this prospective observational study was to evaluate the relationship between changes in pulmonary artery systolic pressure (ΔPASP) and both severity of community‐acquired pneumonia (CAP) and changes in peripheral blood oxygen partial pressure (PaO2). Materials and Methods Seventy‐five consecutive adult patients hospitalized for treatment of CAP were recruited in this single‐center cohort study. Doppler echocardiographic measurement of PASP was performed by 2 staff cardiologists. Follow‐up assessment was performed within 2 to 4 weeks of ending antibiotic treatment at radiographic resolution of CAP. Fifteen patients were excluded during follow‐up due to confirmation of chronic obstructive pulmonary disease. Results Pneumonia was unilateral in 40 (66.7%) and bilateral in 20 (33.3%) patients. Radiographic extent of pneumonia involved 2 pulmonary segments in 31 patients (51.7%), 3 to 5 pulmonary segments in 25 (41.7%), and 6 pulmonary segments in 4 patients (6.6%). ΔPASP between hospital admission and follow‐up correlated with the number of pulmonary segments involved (Rho = 0.953; P