Bidirectional mediation of depression and pain intensity on their associations with upper extremity physical function

Pain intensity and symptoms of depression are correlated and individually associated with decreased physical function. We compared two explanatory mediation models; one with depression as mediator of the association of pain intensity with physical function and the other one with pain intensity as th...

Full description

Saved in:
Bibliographic Details
Published in:Journal of behavioral medicine 2018-06, Vol.41 (3), p.309-317
Main Authors: Talaei-Khoei, Mojtaba, Fischerauer, Stefan F., Jha, Ragini, Ring, David, Chen, Neal, Vranceanu, Ana-Maria
Format: Article
Language:English
Subjects:
Bidirectionality
Complications and side effects
Demography
Depression (Mood disorder)
Exercise
Family Medicine
General Practice
Health Psychology
Language proficiency
Mediation
Medicine
Medicine & Public Health
Mental depression
Pain
Physical ability
Physiological aspects
Psychological aspects
Reinforcement
Symptoms
Upper limbs
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Pain intensity and symptoms of depression are correlated and individually associated with decreased physical function. We compared two explanatory mediation models; one with depression as mediator of the association of pain intensity with physical function and the other one with pain intensity as the mediator of the effect of depression on physical function. In a cross-sectional study, 102 patients with upper extremity musculoskeletal illness completed measures of pain intensity, PROMIS depression CAT, PROMIS physical function-upper extremity CAT and demographics. We determined that pain intensity and symptoms of depression were partial mediators of their respective and independent effects on physical function. While depression had a larger standardized mediation effect and a bigger kappa-squared ( κ 2 ) effect size compared to pain intensity, the actual proportion of variance in physical function that could be explained by the mediated effects (i.e., R 2 mediation effect size) was equal in both models suggesting that the two mediation models have equal ability to explain variations in physical function. The bidirectional mediation effect suggests a reinforcement mechanism, in which, pain intensity and symptoms of depression reciprocally influence their negative impacts on physical function among patients with musculoskeletal illness.
ISSN:0160-7715
1573-3521
DOI:10.1007/s10865-017-9891-6