Short‐ and long‐term evaluation of cognitive functions after electroconvulsive therapy in a Japanese population

Aim While electroconvulsive therapy (ECT) is a well‐established, safe, and effective treatment for mental illnesses, the potential for adverse effects on cognitive functions remains controversial. We aimed to evaluate multiple cognitive functions in different time periods before and after ECT in a J...

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Bibliographic Details
Published in:Psychiatry and clinical neurosciences 2018-02, Vol.72 (2), p.95-102
Main Authors: Takagi, Shunsuke, Takeuchi, Takashi, Yamamoto, Naoki, Fujita, Munehisa, Furuta, Ko, Ishikawa, Hiroyo, Motohashi, Nobutaka, Nishikawa, Toru
Format: Article
Language:English
Subjects:
Cognition
Cognitive ability
cognitive function
depression
Electroconvulsive therapy
Information processing
information processing speed
Side effects
verbal fluency
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Summary:Aim While electroconvulsive therapy (ECT) is a well‐established, safe, and effective treatment for mental illnesses, the potential for adverse effects on cognitive functions remains controversial. We aimed to evaluate multiple cognitive functions in different time periods before and after ECT in a Japanese population. Methods A battery of five neurocognitive tests was administered to patients who underwent a course of ECT treatment at three time points: before, immediately after, and 4 weeks after ECT. Results A transient but significant decline in letter fluency function was observed immediately after ECT, but had recovered well by 4 weeks. We also observed a significant improvement in the trail‐making task at 4 weeks after ECT. Conclusion In a Japanese population, adverse effects of ECT on verbal fluency function‐related and other cognitive impairments were transient. Over the longer term, we detected significant improvements in the performance of tasks that presumably reflected information processing speed and executive functions.
ISSN:1323-1316
1440-1819
DOI:10.1111/pcn.12614