Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017Utility and Limitations

Pan-Assay Interference Compounds (PAINS) are very familiar to medicinal chemists who have spent time fruitlessly trying to optimize these nonprogressible compounds. Electronic filters formulated to recognize PAINS can process hundreds and thousands of compounds in seconds and are in widespread curre...

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Bibliographic Details
Published in:ACS chemical biology 2018-01, Vol.13 (1), p.36-44
Main Authors: Baell, Jonathan B, Nissink, J. Willem M
Format: Article
Language:English
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