Interleukin‐33 (IL‐33): A nuclear cytokine from the IL‐1 family

Summary Interleukin‐33 (IL‐33) is a tissue‐derived nuclear cytokine from the IL‐1 family abundantly expressed in endothelial cells, epithelial cells and fibroblast‐like cells, both during homeostasis and inflammation. It functions as an alarm signal (alarmin) released upon cell injury or tissue dama...

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Bibliographic Details
Published in:Immunological reviews 2018-01, Vol.281 (1), p.154-168
Main Authors: Cayrol, Corinne, Girard, Jean‐Philippe
Format: Article
Language:English
Subjects:
Allergology
allergy
Asthma
CD8 antigen
Cell injury
cytokine
Cytokines
Dendritic cells
Endothelial cells
Eosinophils
Epithelial cells
Fibrosis
Helper cells
Homeostasis
Hypersensitivity
ILC2
IL‐33
Immune response
Immune system
Immunology
Immunoregulation
inflammation
Inflammatory diseases
innate immunity
Interleukin 1
Interleukin 1 receptors
Leukocytes (basophilic)
Leukocytes (eosinophilic)
Leukocytes (neutrophilic)
Life Sciences
Localization
Lymphocytes
Lymphocytes B
Lymphocytes T
Lymphoid cells
Macrophages
Mast cells
Signaling
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