Risk of Subsequent Fragility Fractures Observed After Low-Trauma Ankle Fractures

While fragility fractures (FFs) are one of the strongest predictors of subsequent osteoporotic fractures, it remains unclear whether low-trauma ankle fractures have this ability. The aim of the study was to identify the characteristics of patients with low-trauma ankle FFs who develop subsequent FFs...

Full description

Saved in:
Bibliographic Details
Published in:Calcified tissue international 2018-07, Vol.103 (1), p.62-70
Main Authors: Roux, S., Cabana, F., Carrier, N., Beaulieu, M. C., Boire, G.
Format: Article
Language:English
Subjects:
Ankle
Biochemistry
Biomedical and Life Sciences
Bone mineral density
Cell Biology
Endocrinology
Fractures
Life Sciences
Mechanical properties
Original Research
Orthopedics
Osteoporosis
Patients
Risk assessment
Trauma
Wrist
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:While fragility fractures (FFs) are one of the strongest predictors of subsequent osteoporotic fractures, it remains unclear whether low-trauma ankle fractures have this ability. The aim of the study was to identify the characteristics of patients with low-trauma ankle FFs who develop subsequent FFs. The OPTIMUS initiative is a strategy to improve osteoporosis treatment post-FF in orthopedic clinics. FRAX scores without BMD (FRAX-BMI) were calculated at time of inclusion. Recurrent FFs were recorded over a 48-month follow-up. All FFs were X-ray-confirmed. A total of 265 patients with initial ankle FF were included (190 women; mean age 62.8 ± 9.6 years), of whom 15 developed new FFs. Patients with ankle FFs had longer time until recurrence and lower 2-year incidence of recurrent FFs (3.2%) compared with those having wrist FFs (9.0%) or other initial FFs (9.6%), and 4-year incidence rates of 6.2, 13.4, and 15.3%, respectively (log-rank test, p  = 0.001). With an ankle FF at inclusion, recurrent FFs were more frequent in patients with previous FF (6.2 per 100 patient-years; p  
ISSN:0171-967X
1432-0827
DOI:10.1007/s00223-018-0393-5