Early diagnosis of septic arthritis in immunocompromised patients

Septic arthritis results in rapid joint destruction if not properly diagnosed and treated. A work up for septic arthritis includes a peripheral white blood cell count, inflammatory markers, and a joint aspiration. In the general population, the interpretation of these labs has been well-defined by p...

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Bibliographic Details
Published in:Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2018-05, Vol.23 (3), p.542-545
Main Authors: Butler, Bennet A., Fitz, David W., Lawton, Cort D., Li, Daniel D., Balderama, Earvin S., Stover, Michael D.
Format: Article
Language:English
Subjects:
Arthritis, Infectious - blood
Arthritis, Infectious - diagnosis
Arthritis, Infectious - immunology
Blood Sedimentation
C-Reactive Protein - metabolism
Early Diagnosis
Humans
Immunocompromised Host
Leukocyte Count
Retrospective Studies
Sensitivity and Specificity
Synovial Fluid - metabolism
Synovial Fluid - microbiology
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Summary:Septic arthritis results in rapid joint destruction if not properly diagnosed and treated. A work up for septic arthritis includes a peripheral white blood cell count, inflammatory markers, and a joint aspiration. In the general population, the interpretation of these labs has been well-defined by prior studies. To this point, no study has determined how immunosuppressive states affect this work up. Patients with immunosuppressive conditions who received a joint aspiration for a painful joint were retrospectively identified. Laboratory results from their work up were gathered and analyzed. 216 patients were included in the study, 21 of whom were diagnosed with septic arthritis. The average aspiration WBC count was 74,190 with 88% PMNs. 81% had a positive gram stain. Laboratory values for immunosuppressed patients with septic arthritis were similar to those associated with septic arthritis in historical general population controls.
ISSN:0949-2658
1436-2023
DOI:10.1016/j.jos.2018.02.011