Coffee consumption, metabolic syndrome and clinical severity of psoriasis: good or bad stuff?

Despite the wide consumption of coffee, its anti-inflammatory effect on clinical severity of psoriasis is still debatable. The aim of this study was to evaluate the association between the coffee consumption and clinical severity of psoriasis in a sample of patients stratified according to the prese...

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Bibliographic Details
Published in:Archives of toxicology 2018-05, Vol.92 (5), p.1831-1845
Main Authors: Barrea, Luigi, Muscogiuri, Giovanna, Di Somma, Carolina, Annunziata, Giuseppe, Megna, Matteo, Falco, Andrea, Balato, Anna, Colao, Annamaria, Savastano, Silvia
Format: Article
Language:English
Subjects:
Anthropometry
Biomedical and Life Sciences
Biomedicine
Coffee
Cups
Diet
Energy intake
Environmental Health
Health risk assessment
Inflammation
Metabolic syndrome
Occupational Medicine/Industrial Medicine
Organ Toxicity and Mechanisms
Patients
Pharmacology/Toxicology
Psoriasis
Public health
Smoking
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Summary:Despite the wide consumption of coffee, its anti-inflammatory effect on clinical severity of psoriasis is still debatable. The aim of this study was to evaluate the association between the coffee consumption and clinical severity of psoriasis in a sample of patients stratified according to the presence of the metabolic syndrome (MetS) and smoking. This cross-sectional case–control observational study was conducted on 221 treatment-naïve psoriatic patients. Lifestyle habits, anthropometric measures, clinical and biochemical evaluations were obtained. Clinical severity of psoriasis was assessed by Psoriasis Area and Severity Index (PASI) score. Data on energy caloric intake and coffee consumption were collected using a 7-day food diary record. The coffee consumption was analyzed as coffee intake (consumers and non-consumers) and daily servings (range 0–4 servings/day). Coffee consumers have a lower PASI score vs non-consumers ( p  
ISSN:0340-5761
1432-0738
DOI:10.1007/s00204-018-2193-0