Association of long-term dynamic change in body weight and incident hypertension: The Rural Chinese Cohort Study

•Nearly half of people showed varying degrees of weight gain during the 6-y period and only 7.9% achieved at least a 6% (32.7%). Only 7.9% lost >6% weight. For every 1% increase in relative body weight, systolic and diastolic blood pressures increased 0.27 and 0.22 mm Hg, respectively. Risk for h...

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Published in:Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2018-10, Vol.54, p.76-82
Main Authors: Zhao, Yang, Liu, Yu, Sun, Haohang, Sun, Xizhuo, Yin, Zhaoxia, Li, Honghui, Ren, Yongcheng, Wang, Bingyuan, Zhang, Dongdong, Liu, Xuejiao, Liu, Dechen, Zhang, Ruiyuan, Liu, Feiyan, Chen, Xu, Liu, Leilei, Cheng, Cheng, Zhou, Qionggui, Hu, Dongsheng, Zhang, Ming
Format: Article
Language:English
Subjects:
Adults
Anthropometry
Blood pressure
Body weight
Body weight gain
Body weight loss
Cohort analysis
Dose–response
Epidemiology
Hypertension
Lifestyles
Obesity
Overweight
Regression analysis
Risk
Risk reduction
Rural areas
Statistical analysis
Studies
Weight change
Weight control
Weight loss
Weight reduction
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Summary:•Nearly half of people showed varying degrees of weight gain during the 6-y period and only 7.9% achieved at least a 6% (32.7%). Only 7.9% lost >6% weight. For every 1% increase in relative body weight, systolic and diastolic blood pressures increased 0.27 and 0.22 mm Hg, respectively. Risk for hypertension was reduced and increased with weight loss >6% (OR, 0.78; 95% CI, 0.61–0.99) and gain >6% (OR, 2.08; 95% CI, 1.79–2.42), respectively, compared with weight loss or gain ≤3%. With baseline prehypertension, compared with maintaining a stable weight, weight loss >6% reduced the risk for hypertension (OR, 0.71; 95% CI, 0.54–0.95). With baseline overweight, compared with maintaining the overweight status during follow-up, changing to normal weight reduced the risk for hypertension (OR, 0.67; 95% CI, 0.49–0.92), but changing to general obesity increased the risk (OR, 1.73; 95% CI, 1.35–2.22). Long-term excessive weight gain is positively associated with increased risk for incident hypertension. Losing weight by lifestyle modification could be helpful for the primary prevention of hypertension in the general rural Chinese population.
ISSN:0899-9007
1873-1244
DOI:10.1016/j.nut.2018.02.020