A meta-analysis of reduced leaflet motion for surgical and transcatheter aortic valves: Relationship to cerebrovascular events and valve degeneration

Reduced leaflet motion (RLM) of transcatheter aortic valves (TAV) is observed in up to 4% of cases with similar frequency in surgical valves, with an overall incidence that differs based on prosthesis type and size. This phenomenon likely represents subclinical leaflet thrombosis. Herein we sought t...

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Bibliographic Details
Published in:Cardiovascular revascularization medicine 2018-10, Vol.19 (7), p.868-873
Main Authors: Makki, Nader, Shreenivas, Satya, Kereiakes, Dean, Lilly, Scott
Format: Article
Language:English
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Summary:Reduced leaflet motion (RLM) of transcatheter aortic valves (TAV) is observed in up to 4% of cases with similar frequency in surgical valves, with an overall incidence that differs based on prosthesis type and size. This phenomenon likely represents subclinical leaflet thrombosis. Herein we sought to analyze the existing reported literature to assess whether or not RLM is associated with subsequent valve degeneration or cerebrovascular events. We searched PubMed, and EMBASE (2008–2017) to identify relevant studies. Studies with 20 mm Hg.•Out of 30 studies, six observational studies with a total population of 1,704 patients met our selection criteria. RLM was associated with an increased risk of stroke or TIA (adjusted OR 2.60, 95% CI 1.56 to 4.34, p = 0.004). At one y
ISSN:1553-8389
1878-0938
DOI:10.1016/j.carrev.2018.03.003