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Preparation and characterization of iron oxide magnetic nanoparticles functionalized by nisin
The average size parameters of nisin-loaded iron oxide nanoparticle stabilized with acids. [Display omitted] •Iron oxide magnetic nanoparticles were synthesized and characterized.•They were stabilized by citric, ascorbic gallic or glucuronic acid coating.•Nanoparticles were functionalized by nisin u...
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Published in: | Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2018-09, Vol.169, p.126-134 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | The average size parameters of nisin-loaded iron oxide nanoparticle stabilized with acids.
[Display omitted]
•Iron oxide magnetic nanoparticles were synthesized and characterized.•They were stabilized by citric, ascorbic gallic or glucuronic acid coating.•Nanoparticles were functionalized by nisin using a simple adsorption method.
Nisin is a known bacteriocin approved as a food additive for food preservation. It exhibits a wide spectrum antimicrobial activity against Gram-positive bacteria. Iron oxide magnetic nanoparticles were synthesized and characterized by X-ray diffraction method. A main part of iron oxide nanoparticles was found to be maghemite though a small quantity of magnetite could also be present. Magnetic nanoparticles were stabilized by citric, ascorbic, gallic or glucuronic acid coating. Stable iron oxide magnetic nanoparticles were functionalized by nisin using a simple and low cost adsorption method. Nisin loading was confirmed by FT-IR spectra, thermogravimetric analysis, dynamic light scattering and atomic force microscopy methods. Nisin-loaded iron oxide magnetic nanoparticles were stable at least six weeks as judged by the measurements of zeta-potential and hydrodynamic diameter. The antimicrobial activity of nisin-loaded iron oxide magnetic nanoparticles was demonstrated toward Gram-positive bacteria. Functionalized nanoparticles could therefore find the application as antimicrobials in innovative and emerging technologies based on the magnetic field. |
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ISSN: | 0927-7765 1873-4367 |
DOI: | 10.1016/j.colsurfb.2018.05.017 |