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Identification of cytotoxic constituent of Indonesian sponge Kaliapsis sp. (Bowerbank)
Identification of cytotoxic constituent of Indonesian sponge Kaliapsis sp. has been conducted. The structure identification was judged based on the spectroscopic data, namely, ultraviolet, MS, one and two-dimensional 1H-NMR and 13C-NMR methods. The cytotoxic constituent was identified as 1-(tetrahyd...
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| Published in: | Pakistan journal of biological sciences 2008-11, Vol.11 (22), p.2560-2566 |
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| Main Authors: | , , , , |
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| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c249t-b1adfcdc15169795a8403a2530b5e8d05e47a5c5e137f4c95bed0b28137d0d893 |
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| cites | cdi_FETCH-LOGICAL-c249t-b1adfcdc15169795a8403a2530b5e8d05e47a5c5e137f4c95bed0b28137d0d893 |
| container_end_page | 2566 |
| container_issue | 22 |
| container_start_page | 2560 |
| container_title | Pakistan journal of biological sciences |
| container_volume | 11 |
| creator | Setyowati, E P Jenie, U A Sudarsono Kardono, L B S Rahmat, R |
| description | Identification of cytotoxic constituent of Indonesian sponge Kaliapsis sp. has been conducted. The structure identification was judged based on the spectroscopic data, namely, ultraviolet, MS, one and two-dimensional 1H-NMR and 13C-NMR methods. The cytotoxic constituent was identified as 1-(tetrahydro-4-hydroxy-5-(hydroxymethyl)furan-2-yl)-5-methyl pyrimidine-2,4(1H,3H)-dione. This constituent hasn't been isolated from sponges as natural product. |
| doi_str_mv | 10.3923/pjbs.2008.2560.2566 |
| format | article |
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(Bowerbank)</title><title>Pakistan journal of biological sciences</title><addtitle>Pak J Biol Sci</addtitle><description>Identification of cytotoxic constituent of Indonesian sponge Kaliapsis sp. has been conducted. The structure identification was judged based on the spectroscopic data, namely, ultraviolet, MS, one and two-dimensional 1H-NMR and 13C-NMR methods. The cytotoxic constituent was identified as 1-(tetrahydro-4-hydroxy-5-(hydroxymethyl)furan-2-yl)-5-methyl pyrimidine-2,4(1H,3H)-dione. 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(Bowerbank)</atitle><jtitle>Pakistan journal of biological sciences</jtitle><addtitle>Pak J Biol Sci</addtitle><date>2008-11-15</date><risdate>2008</risdate><volume>11</volume><issue>22</issue><spage>2560</spage><epage>2566</epage><pages>2560-2566</pages><issn>1028-8880</issn><abstract>Identification of cytotoxic constituent of Indonesian sponge Kaliapsis sp. has been conducted. The structure identification was judged based on the spectroscopic data, namely, ultraviolet, MS, one and two-dimensional 1H-NMR and 13C-NMR methods. The cytotoxic constituent was identified as 1-(tetrahydro-4-hydroxy-5-(hydroxymethyl)furan-2-yl)-5-methyl pyrimidine-2,4(1H,3H)-dione. This constituent hasn't been isolated from sponges as natural product.</abstract><cop>Pakistan</cop><pmid>19260333</pmid><doi>10.3923/pjbs.2008.2560.2566</doi><tpages>7</tpages></addata></record> |
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| ispartof | Pakistan journal of biological sciences, 2008-11, Vol.11 (22), p.2560-2566 |
| issn | 1028-8880 |
| language | eng |
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| source | EZB Electronic Journals Library |
| subjects | Animals Biological Products - chemistry Biological Products - isolation & purification Biological Products - pharmacology Cell Line, Tumor Cell Proliferation - drug effects Cytotoxins - chemistry Cytotoxins - isolation & purification Cytotoxins - pharmacology Furans - chemistry Furans - isolation & purification Furans - pharmacology HeLa Cells Humans Indonesia Inhibitory Concentration 50 Magnetic Resonance Spectroscopy Mass Spectrometry Molecular Structure Porifera Porifera - chemistry Pyrimidines - chemistry Pyrimidines - isolation & purification Pyrimidines - pharmacology Solubility Spectrophotometry, Infrared Thymine - analogs & derivatives Thymine - chemistry Thymine - isolation & purification Thymine - pharmacology Transition Temperature |
| title | Identification of cytotoxic constituent of Indonesian sponge Kaliapsis sp. (Bowerbank) |
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