Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding the genetic factors contributing to the shared and disorder-specific symptoms will be crucial for improving diagnosis and treatment. In genetic data consisting of 53,555 cases (20,129 bipolar disorde...

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Published in:	Cell 2018-06, Vol.173 (7), p.1705-1715.e16
Main Authors:	Ruderfer, Douglas M., Boocock, James, Stahl, Eli A., Charney, Alexander W., Ori, Anil P.S., Alliey-Rodriguez, Ney, Anjorin, Adebayo, Badner, Judith A., Band, Gavin, Bruggeman, Richard, Buccola, Nancy G., Bumpstead, Suzannah J., Casas, Juan P., Chan, Raymond C.K., Chen, Ronald Y.L., Collier, David A., Cormican, Paul, Craddock, Nicholas, Crowley, James J., Curtis, David, Dannlowski, Udo, Davidson, Michael, Demontis, Ditte, Dronov, Serge, Elvsashagen, Torbjorn, Etain, Bruno, Fan, Chun Chieh, Forty, Liz, Fraser, Christine, Garnham, Julie, Gill, Michael, Gillman, Matthew, Gratten, Jacob, Gwilliam, Rhian, Hammer, Christian, Hansen, Thomas, Henskens, Frans A., Jamain, Stephane, Jankowski, Janusz, Joa, Inge, Julia, Antonio, Kandaswamy, Radhika, Kavanagh, David, Keller, Matthew C., Khrunin, Andrey, Lee, Phil H., Legge, Sophie E., Lencz, Todd, Levinson, Douglas F., Levy, Shawn E., Li, Tao, Lin, Kuang, Macek, Milan, McCarley, Robert W., McGuffin, Peter, McInnis, Melvin G., Meijer, Carin J., Melegh, Bela, Mesholam-Gately, Raquelle I., Myin-Germeys, Inez, Nicodemus, Kristin K., Nimgaonkar, Vishwajit, Nordin, Annelie, Nöthen, Markus M., Van Os, Jim, Owen, Michael J., Palmer, Colin N.A., Palotie, Aarno, Papadimitriou, George N., Pato, Michele T., Perlis, Roy H., Petryshen, Tracey L., Plomin, Robert, Potash, James B., Powell, John, Ramos-Quiroga, Josep Antoni, Rautanen, Anna, Reichenberg, Abraham, Ribases, Marta, Rice, John P., Richards, Alexander L., Ricketts, Michelle, Sanchez-Mora, Cristina, Sanders, Alan R., Schall, Ulrich, Serretti, Alessandro, Sham, Pak C., Straub, Richard E., Strauss, John S., Szatkiewicz, Jin P., Thompson, Robert C., Thorgeirsson, Thorgeir E., Treutlein, Jens, Vedder, Helmut, Wang, Qiang, Wu, Jing Qin, Sullivan, Patrick F., Wray, Naomi R., Sklar, Pamela, Kendler, Kenneth S.
Format:	Article
Language:	English
Subjects:	bipolar disorder Bipolar Disorder - genetics Bipolar Disorder - pathology Case-Control Studies genes genetic factors Genetic Loci Genome-Wide Association Study genomics Humans loci Multifactorial Inheritance - genetics neurons Odds Ratio Phenotype polygenic risk potassium psychosis Risk schizophrenia Schizophrenia - genetics Schizophrenia - pathology subphenotypes White People - genetics
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